Search ↗

Clinics · Comparison

Defy Medical vs Hone Health

Both are primarily TRT & men’s hormones providers, so the differences are in consult model, what is bundled, who prescribes, and price.

Defy Medical logo Defy Medical From Under $175/mo average for TRT in year one Read the Defy Medical review →
vs
Hone Health logo Hone Health From $65 initial lab test Read the Hone Health review →

Side-by-side comparison

Defy Medical logoDefy MedicalHone Health logoHone Health
Our score6.8* / 106.2* / 10
Starting priceUnder $175/mo average for TRT in year one$65 initial lab test
Primary serviceTRT & men’s hormonesTRT & men’s hormones
All servicesTRT, Peptides, HRT, EDTRT, Bloodwork, GLP-1
Consult modelLive video consultLive video consult
PrescriberMD/DO + NP/PAMD/DO
LabsBilled separatelyBilled separately
InsuranceCash payCash pay
AvailabilityUnconfirmedUnconfirmed
CancellationNo subscription to cancelBy email or written request
Trustpilot4.8 / 5 (4,221 reviews)4.8 / 5 (12,416 reviews)
Regulatory / legal recordNone foundNone found
Visit ↗Visit ↗

* Provisional score: one or two criteria could not be verified.

Which one is right for you

Choose Defy Medical if…

Self-pay patients who want long video consultations and a la carte hormone, weight-loss or peptide care without a subscription, and who can tolerate unpublished per-visit pricing.

  • No subscription, monthly fee or contract; patients pay only for the services they buy
  • Initial consultations by secure video last up to one hour, and follow-ups up to 30 minutes
  • Care team of physicians, physician assistants and nurse practitioners, plus an in-person clinic in Tampa

Choose Hone Health if…

Men or women who want a physician-led video consult and regular biomarker retesting across hormones, weight and longevity, and are fine paying a membership plus medication.

  • Prices for membership tiers, the initial lab test and most individual medications are listed on the site
  • Initial consult is a live 45-minute video visit with a licensed physician
  • Trustpilot 4.8 from 12,416 reviews; BBB A+ and accredited

Price: what you actually pay

Defy Medical

Defy's FAQ estimates male TRT averages under $175/month in the first year and about $125/month after that. The estimate covers testosterone, a weekly aromatase inhibitor, labs and consultations, and Defy says it is not a price guarantee. There is no monthly fee: consultations, labs and medications are each paid for when bought. No consultation fee is published on Defy's site.

Hone Health

The first step is a $65 50+ biomarker test plus physician consult; the how-it-works page also shows a $25 onboarding fee next to the $25 Basic plan. Basic ($25/mo) covers testing every 6 months and lets you buy consults. Premium ($155/mo) adds testing every 3 months, physician consults and all treatments. Medication is extra, e.g. testosterone injections 'From $28/mo + membership', testosterone cream 'From $60/mo + membership', enclomiphene 'From $42/mo + membership'.

What happens after you sign up

Defy Medical

Treatments offered: Testosterone (TRT), Trimix (compounded injectable for ED), Semaglutide, Tirzepatide, Sermorelin, Ketamine, Bioidentical hormones (BHRT) for women, Thyroid medication, BPC-157, TB-500, Epitalon, KPV, MOTS-c. Prescribers: MD/DO + NP/PA.

Hone Health

Treatments offered: Testosterone (injection, cream, troches), Enclomiphene, Clomiphene citrate, Anastrozole, Tadalafil, Sildenafil, PT-141 (bremelanotide), Finasteride + minoxidil, Naltrexone, Low-dose naltrexone, Bupropion, Phentermine, Topiramate, Sermorelin, Compounded liraglutide, Metformin, Omega-3-acid ethyl esters, NAD+, Vitamin B12, Glutathione, Estradiol (patch, cream), Bi-est cream, Progesterone (oral, cream). Prescribers: MD/DO.

Cancelling and refunds

Defy Medical

No subscription or contract: 'Defy Medical doesn't lock patients into subscriptions or contracts', and charges are due when a service is purchased, so there is no recurring plan to cancel. Appointments cancelled with less than 24 hours' notice, and no-shows, may be charged the full consultation fee. Sales are generally final. Lab orders are refundable only before specimens are submitted, and dispensed medications are not refundable.

Hone Health

Terms of Use: subscriptions auto-renew. Cancel before the end of the current period via a help-center request form, by calling (833) 444-4483, or by emailing support@honehealth.com. The account closes at the end of the billing period. 'Your subscription can be cancelled at any time, but any fees paid to Hone or its affiliated-medical practices are not refundable.' The homepage says 'No commitments. Cancel anytime.' Lab fees are billed at the lab's rates and refunds are up to the lab.

Where each is available

Defy Medical

Says telemedicine is offered in 'most states throughout the US' without listing them. Its lab-ordering site (testdefy.com) says on-demand lab testing is not offered in NY, NJ, PA, RI or MA. The ToS says controlled-substance prescriptions are not sent across state lines.

Hone Health

Not published.

Full breakdown of each

#1 Defy Medical logo

Self-pay patients who want long video consultations and a la carte hormone, weight-loss or peptide care without a subscription, and who can tolerate unpublished per-visit pricing.

Starting price
Under $175/mo average for TRT in year one
Consult model
Live video consult
Prescriber
MD/DO + NP/PA
Labs
Billed separately
Insurance
Cash pay
Availability
Unconfirmed
Cancellation
No subscription to cancel
Founded
Tampa, FL

Pricing

Defy's FAQ estimates male TRT averages under $175/month in the first year and about $125/month after that. The estimate covers testosterone, a weekly aromatase inhibitor, labs and consultations, and Defy says it is not a price guarantee. There is no monthly fee: consultations, labs and medications are each paid for when bought. No consultation fee is published on Defy's site.

Prices as listed on October 17, 2026. They change often; confirm at checkout.

What we like

  • No subscription, monthly fee or contract; patients pay only for the services they buy
  • Initial consultations by secure video last up to one hour, and follow-ups up to 30 minutes
  • Care team of physicians, physician assistants and nurse practitioners, plus an in-person clinic in Tampa
  • Trustpilot score of 4.8 from 4,221 reviews

Watch out for

  • No consultation, lab or medication prices on the main site; only an average monthly TRT estimate
  • Does not accept insurance of any kind (it provides a superbill on request)
  • Its Peptide Therapy service page features BPC-157, TB-500, Epitalon, KPV and MOTS-c, which are on FDA's 503A Category 2 safety-risk list
  • BBB rating of C- (not accredited), with 4 complaints in the last 3 years
Treatments offered
Testosterone (TRT)Trimix (compounded injectable for ED)SemaglutideTirzepatideSermorelinKetamineBioidentical hormones (BHRT) for womenThyroid medicationBPC-157TB-500EpitalonKPVMOTS-c
Cancelling

No subscription or contract: 'Defy Medical doesn't lock patients into subscriptions or contracts', and charges are due when a service is purchased, so there is no recurring plan to cancel. Appointments cancelled with less than 24 hours' notice, and no-shows, may be charged the full consultation fee. Sales are generally final. Lab orders are refundable only before specimens are submitted, and dispensed medications are not refundable.

Where it is available

Says telemedicine is offered in 'most states throughout the US' without listing them. Its lab-ordering site (testdefy.com) says on-demand lab testing is not offered in NY, NJ, PA, RI or MA. The ToS says controlled-substance prescriptions are not sent across state lines.

#2 Hone Health logo

Men or women who want a physician-led video consult and regular biomarker retesting across hormones, weight and longevity, and are fine paying a membership plus medication.

Starting price
$65 initial lab test
Consult model
Live video consult
Prescriber
MD/DO
Labs
Billed separately
Insurance
Cash pay
Availability
Unconfirmed
Cancellation
By email or written request
Founded
2020 · New York, NY

Pricing

The first step is a $65 50+ biomarker test plus physician consult; the how-it-works page also shows a $25 onboarding fee next to the $25 Basic plan. Basic ($25/mo) covers testing every 6 months and lets you buy consults. Premium ($155/mo) adds testing every 3 months, physician consults and all treatments. Medication is extra, e.g. testosterone injections 'From $28/mo + membership', testosterone cream 'From $60/mo + membership', enclomiphene 'From $42/mo + membership'.

Prices as listed on October 17, 2026. They change often; confirm at checkout.

What we like

  • Prices for membership tiers, the initial lab test and most individual medications are listed on the site
  • Initial consult is a live 45-minute video visit with a licensed physician
  • Trustpilot 4.8 from 12,416 reviews; BBB A+ and accredited
  • Broad menu covering TRT, fertility-preserving options (enclomiphene, clomiphene), weight loss, ED, hair loss and menopause

Watch out for

  • Medication is billed on top of the membership, so total TRT cost is roughly $28-60/mo in medication plus $155/mo Premium
  • Initial bloodwork is a separate $65 purchase, not bundled into the membership
  • Fees paid are non-refundable under the Terms of Use
  • 125 BBB complaints filed in the last 3 years (per BBB profile)
Treatments offered
Testosterone (injection, cream, troches)EnclomipheneClomiphene citrateAnastrozoleTadalafilSildenafilPT-141 (bremelanotide)Finasteride + minoxidilNaltrexoneLow-dose naltrexoneBupropionPhentermineTopiramateSermorelinCompounded liraglutideMetforminOmega-3-acid ethyl estersNAD+Vitamin B12GlutathioneEstradiol (patch, cream)Bi-est creamProgesterone (oral, cream)
Cancelling

Terms of Use: subscriptions auto-renew. Cancel before the end of the current period via a help-center request form, by calling (833) 444-4483, or by emailing support@honehealth.com. The account closes at the end of the billing period. 'Your subscription can be cancelled at any time, but any fees paid to Hone or its affiliated-medical practices are not refundable.' The homepage says 'No commitments. Cancel anytime.' Lab fees are billed at the lab's rates and refunds are up to the lab.

Defy Medical vs Hone Health: common questions

Is Defy Medical or Hone Health better?

Defy Medical ranks higher on our rubric (6.8* vs 6.2* out of 10; * means provisional, and fully verified scores rank first). That reflects price transparency, labs, availability, cancellation terms and treatment range, not clinical outcomes. Defy Medical: Self-pay patients who want long video consultations and a la carte hormone, weight-loss or peptide care without a subscription, and who can tolerate unpublished per-visit pricing. Hone Health: Men or women who want a physician-led video consult and regular biomarker retesting across hormones, weight and longevity, and are fine paying a membership plus medication.

Which is cheaper, Defy Medical or Hone Health?

Defy Medical starts at Under $175/mo average for TRT in year one (company estimate, pay-per-service). Hone Health starts at $65 initial lab test + consult, then $25/mo (Basic) or $155/mo (Premium) plus medication. Compare what each price includes, especially labs and medication.

Do Defy Medical and Hone Health include lab work?

Defy Medical: billed separately. Hone Health: billed separately.

Which is easier to cancel?

Defy Medical: No subscription or contract: 'Defy Medical doesn't lock patients into subscriptions or contracts', and charges are due when a service is purchased, so there is no recurring plan to cancel. Appointments cancelled with less than 24 hours' notice, and no-shows, may be charged the full consultation fee. Sales are generally final. Lab orders are refundable only before specimens are submitted, and dispensed medications are not refundable. Hone Health: Terms of Use: subscriptions auto-renew. Cancel before the end of the current period via a help-center request form, by calling (833) 444-4483, or by emailing support@honehealth.com. The account closes at the end of the billing period. 'Your subscription can be cancelled at any time, but any fees paid to Hone or its affiliated-medical practices are not refundable.' The homepage says 'No commitments. Cancel anytime.' Lab fees are billed at the lab's rates and refunds are up to the lab.

Can Defy Medical or Hone Health prescribe treatment?

Defy Medical: yes (Testosterone (TRT), Trimix (compounded injectable for ED), Semaglutide, Tirzepatide). Hone Health: yes (Testosterone (injection, cream, troches), Enclomiphene, Clomiphene citrate, Anastrozole).

Sources

Regulatory and primary sources

  1. Defy Medical: Defy Medical homepage ↗
  2. Defy Medical: Peptide Therapy - Defy Medical ↗
  3. Defy Medical: About Defy Medical ↗
  4. Defy Medical: Defy Medical Terms of Service ↗
  5. Defy Medical: Get Started - Defy Medical ↗
  6. Defy Medical: How much does TRT cost with Defy Medical? ↗
  7. Defy Medical: What Does a Typical Telemedicine Hormone Therapy Appointment Look Like? ↗
  8. Defy Medical: Defy Medical Tampa Clinic ↗
  9. Defy Medical: Lab Tests Online - Defy Medical ↗
  10. Defy Medical: TestDefy lab ordering ↗
  11. Defy Medical: Defy Medical Patient Specials 2025 ↗
  12. Defy Medical: Defy Medical Trustpilot ↗
  13. Defy Medical: Defy Medical LLC BBB profile ↗
  14. Hone Health: Hone Health homepage ↗
  15. Hone Health: Hone How It Works (pricing table, FAQ) ↗
  16. Hone Health: Hone TRT treatments ↗
  17. Hone Health: Hone weight loss treatments ↗
  18. Hone Health: Hone longevity treatments ↗
  19. Hone Health: Hone ED treatments ↗
  20. Hone Health: Hone hair loss treatments ↗
  21. Hone Health: Hone menopause treatments ↗
  22. Hone Health: Hone Consults ↗
  23. Hone Health: Hone Terms of Use ↗
  24. Hone Health: Hone About (address, founder) ↗
  25. Hone Health: Hone Health Trustpilot ↗
  26. Hone Health: BBB profile: Hone (Time Therapeutics, Inc.) ↗
  27. Hone Health: Pulse 2.0 interview with Hone CEO Saad Alam ↗
  28. Hone Health: MedCity News: Hone Health secures $33M, acquires ivee ↗
  29. Lindy Health clinic scoring rubric ↗