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Clinic review · TRT & men’s hormones

Defy Medical review

One of the longest-running hormone telehealth clinics, offering TRT, HRT for women, peptide therapy and sexual health treatments with physician oversight.

By Lindy Health editorial Researched October 17, 2026 13 sources cited No commercial relationship

The verdict

Self-pay patients who want long video consultations and a la carte hormone, weight-loss or peptide care without a subscription, and who can tolerate unpublished per-visit pricing.

Visit defymedical.com ↗
Starts atUnder $175/mo average for TRT in year one
PrescriberMD/DO + NP/PA
LabsExtra cost
AvailabilityUnconfirmed
CancellingNo subscription to cancel
InsuranceCash pay
Peptides without a legal compounding route Sources we reviewed describe Defy Medical offering BPC-157, TB-500, Epitalon, KPV, MOTS-c. As of October 2026, FDA lists none of these as approved or on its 503A bulks list, so US compounding pharmacies have no routine legal path to prepare them. Ask the provider exactly what is prescribed and which pharmacy makes it. The sources are listed at the foot of this page.

Defy Medical at a glance

Consult modelLive video consult
PrescriberMD/DO + NP/PA
LabsBilled separately
InsuranceCash pay only
AvailabilityNot confirmed from published pages
CancellationNo subscription to cancel
HeadquartersTampa, FL

How much does Defy Medical cost?

From Under $175/mo average for TRT in year one (company estimate, pay-per-service). Defy's FAQ estimates male TRT averages under $175/month in the first year and about $125/month after that. The estimate covers testosterone, a weekly aromatase inhibitor, labs and consultations, and Defy says it is not a price guarantee. There is no monthly fee: consultations, labs and medications are each paid for when bought. No consultation fee is published on Defy's site.

Price transparency on our rubric: Some prices published. Prices were checked on October 17, 2026 and change often; confirm at checkout.

Defy Medical pros and cons

Pros

  • No subscription, monthly fee or contract; patients pay only for the services they buy
  • Initial consultations by secure video last up to one hour, and follow-ups up to 30 minutes
  • Care team of physicians, physician assistants and nurse practitioners, plus an in-person clinic in Tampa
  • Trustpilot score of 4.8 from 4,221 reviews

Cons

  • No consultation, lab or medication prices on the main site; only an average monthly TRT estimate
  • Does not accept insurance of any kind (it provides a superbill on request)
  • Its Peptide Therapy service page features BPC-157, TB-500, Epitalon, KPV and MOTS-c, which are on FDA's 503A Category 2 safety-risk list
  • BBB rating of C- (not accredited), with 4 complaints in the last 3 years

How Defy Medical scores

Defy Medical scores 6.9 out of 10 on the six criteria every clinic is scored on. This score is provisional: we could not verify licensed states from published pages, so that criterion is left out of the average.

Licensed states 20% ?
Labs included 20% 3.0
Prescriber 15% 7.0
Cost transparency 15% 6.0
Cancellation 15% 10.0
Formulary breadth 15% 10.0

n/a = not applicable to this kind of provider · ? = not verifiable from published pages. How each criterion is scored.

What Defy Medical prescribes

  • Testosterone (TRT)
  • Trimix (compounded injectable for ED)
  • Semaglutide
  • Tirzepatide
  • Sermorelin
  • Ketamine
  • Bioidentical hormones (BHRT) for women
  • Thyroid medication
  • BPC-157
  • TB-500
  • Epitalon
  • KPV
  • MOTS-c

In our compound directory: hCG, Sermorelin, PT-141.

How to cancel Defy Medical

No subscription to cancel. No subscription or contract: 'Defy Medical doesn't lock patients into subscriptions or contracts', and charges are due when a service is purchased, so there is no recurring plan to cancel. Appointments cancelled with less than 24 hours' notice, and no-shows, may be charged the full consultation fee. Sales are generally final. Lab orders are refundable only before specimens are submitted, and dispensed medications are not refundable.

Editor’s note: Pay per service with no subscription or contract, per Defy’s own terms.

Is Defy Medical available in my state?

Not confirmed from published pages. Says telemedicine is offered in 'most states throughout the US' without listing them. Its lab-ordering site (testdefy.com) says on-demand lab testing is not offered in NY, NJ, PA, RI or MA. The ToS says controlled-substance prescriptions are not sent across state lines.

What customers say about Defy Medical

PlatformRatingDetail
Trustpilot ↗4.8 / 54,221 reviews
Better Business Bureau ↗C-Not accredited

Third-party ratings as shown on October 17, 2026. They are not part of our score, and review platforms can be gamed in both directions.

We found no FDA warning letters, FTC actions, state board actions or class actions against Defy Medical in our search on October 17, 2026. That is not proof that none exist.

Who Defy Medical is best for

Self-pay patients who want long video consultations and a la carte hormone, weight-loss or peptide care without a subscription, and who can tolerate unpublished per-visit pricing.

Highest-scoring alternatives for TRT & men’s hormones: Marek Health (7.1), Blokes (6.3), OneTwenty (9.2), Male Excel (8.2).

Defy Medical FAQ

How much does Defy Medical cost?

Defy Medical starts at Under $175/mo average for TRT in year one (company estimate, pay-per-service). Defy's FAQ estimates male TRT averages under $175/month in the first year and about $125/month after that. The estimate covers testosterone, a weekly aromatase inhibitor, labs and consultations, and Defy says it is not a price guarantee. There is no monthly fee: consultations, labs and medications are each paid for when bought. No consultation fee is published on Defy's site.

Does Defy Medical take insurance?

No. Defy Medical is cash pay. Some patients use their own insurance at an outside pharmacy for branded medication.

Is Defy Medical legit?

Defy Medical is an operating US telehealth provider, based in Tampa, FL. Prescriptions are written by licensed clinicians (MD/DO + NP/PA). We found no regulatory actions in our search. Trustpilot rates it 4.8/5 from 4,221 reviews.

How do I cancel Defy Medical?

No subscription or contract: 'Defy Medical doesn't lock patients into subscriptions or contracts', and charges are due when a service is purchased, so there is no recurring plan to cancel. Appointments cancelled with less than 24 hours' notice, and no-shows, may be charged the full consultation fee. Sales are generally final. Lab orders are refundable only before specimens are submitted, and dispensed medications are not refundable.

Is Defy Medical available in all states?

Says telemedicine is offered in 'most states throughout the US' without listing them. Its lab-ordering site (testdefy.com) says on-demand lab testing is not offered in NY, NJ, PA, RI or MA. The ToS says controlled-substance prescriptions are not sent across state lines.

Does Defy Medical include lab work?

Billed separately.

Who prescribes at Defy Medical?

A mix of physicians (MD/DO) and nurse practitioners or physician assistants.

Sources

Regulatory and primary sources

  1. Defy Medical homepage ↗ · supports: url, stillOperating, medications
  2. Peptide Therapy - Defy Medical ↗ · supports: fdaBarredOffered, medications, cons
  3. About Defy Medical ↗ · supports: statesDetail, hq
  4. Defy Medical Terms of Service ↗ · supports: insurance, cancellationDetail, statesDetail, hq, cons
  5. Get Started - Defy Medical ↗ · supports: priceDetail, pros
  6. How much does TRT cost with Defy Medical? ↗ · supports: priceFrom, priceDetail, costPublished, cancellationDetail, pros
  7. What Does a Typical Telemedicine Hormone Therapy Appointment Look Like? ↗ · supports: model, prescriberModel, pros
  8. Defy Medical Tampa Clinic ↗ · supports: hq, pros
  9. Lab Tests Online - Defy Medical ↗ · supports: labsIncluded
  10. TestDefy lab ordering ↗ · supports: statesDetail, labsIncluded, costPublished
  11. Defy Medical Patient Specials 2025 ↗ · supports: labsIncluded
  12. Defy Medical Trustpilot ↗ · supports: ratings, pros
  13. Defy Medical LLC BBB profile ↗ · supports: ratings, hq, cons
  14. Lindy Health clinic scoring rubric ↗ · the six criteria, their weights and the scoring tables

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