OneTwenty at a glance
How much does OneTwenty cost?
From $499/yr membership ($749/yr in NY/NJ); medications from $49/mo extra. The annual membership includes a 101-marker baseline panel plus three targeted 20-40 marker follow-up panels, device integration, AI health score, a health coach and custom supplements. Prescription medications are billed monthly or quarterly 'from $49/mo, on top of the annual membership'. The site says 'Founding pricing ends at public launch', so $499 may be a founding-member rate.
Price transparency on our rubric: Some prices published. Prices were checked on October 17, 2026 and change often; confirm at checkout.
OneTwenty pros and cons
Pros
- Four lab panels a year (101-marker baseline plus three follow-ups) are included in the membership price
- Price is published up front: $499/yr ($749/yr in NY/NJ), with medications 'from $49/mo'
- Lists 49 states (all but Rhode Island)
Cons
- The annual membership is non-refundable after a 7-day window, and only if no service has started (3% fee applies)
- Not a medical practice: prescriptions come from unnamed third-party telehealth providers, and the site does not say whether they are physicians or NPs or whether visits are by video
- Early-stage company: it opened a closed beta of 25 founding members in December 2025, and the site says founding pricing ends at public launch
- No direct insurance billing (HSA/FSA reimbursement only)
How OneTwenty scores
OneTwenty scores 9.2 out of 10 on the six criteria every clinic is scored on. This score is provisional: we could not verify prescriber from published pages, so that criterion is left out of the average.
n/a = not applicable to this kind of provider · ? = not verifiable from published pages. How each criterion is scored.
What OneTwenty prescribes
- Enclomiphene
- Compounded semaglutide
- Tirzepatide
- Sermorelin
- Sildenafil
- Tadalafil
- PT-141 (bremelanotide)
- Oxytocin nasal spray
- Metformin
- NAD+ (injection and nasal spray)
- Glutathione (injection and nasal spray)
- GHK-Cu cream
In our compound directory: Semaglutide, Tirzepatide, Sermorelin, Tesamorelin, Gonadorelin.
How to cancel OneTwenty
Self-serve online. Payment and Refund Policy (updated 2026-07-28): cancel via the option in account settings or by emailing support@onetwenty.com. The annual membership renews automatically. A refund is available only within 7 days of purchase and only if no service has started, minus a 3% fee. After that the annual fee is non-refundable, except for a discretionary prorated refund if no lab is reachable. Medication add-ons are non-refundable once prescribed.
Is OneTwenty available in my state?
49 states. Site FAQ: 'available in 49 states except for Rhode Island'; NY and NJ carry a higher fee ($749/yr) because of state lab-draw rules. DC not mentioned.
Regulatory and legal history
We found no FDA warning letters, FTC actions, state board actions or class actions against OneTwenty in our search on October 17, 2026. That is not proof that none exist.
Who OneTwenty is best for
People who mainly want frequent longevity lab testing and wearable data tracking, accept an upfront non-refundable annual fee, and treat prescriptions as an optional add-on.
Highest-scoring alternatives for bloodwork & longevity: InsideTracker (10.0), Superpower (8.9), Marek Health (7.1), Hone Health (6.9).
OneTwenty FAQ
How much does OneTwenty cost?
OneTwenty starts at $499/yr membership ($749/yr in NY/NJ); medications from $49/mo extra. The annual membership includes a 101-marker baseline panel plus three targeted 20-40 marker follow-up panels, device integration, AI health score, a health coach and custom supplements. Prescription medications are billed monthly or quarterly 'from $49/mo, on top of the annual membership'. The site says 'Founding pricing ends at public launch', so $499 may be a founding-member rate.
Does OneTwenty take insurance?
No. OneTwenty is cash pay. Some patients use their own insurance at an outside pharmacy for branded medication.
Is OneTwenty legit?
OneTwenty is an operating US telehealth provider. We found no regulatory actions in our search.
How do I cancel OneTwenty?
Payment and Refund Policy (updated 2026-07-28): cancel via the option in account settings or by emailing support@onetwenty.com. The annual membership renews automatically. A refund is available only within 7 days of purchase and only if no service has started, minus a 3% fee. After that the annual fee is non-refundable, except for a discretionary prorated refund if no lab is reachable. Medication add-ons are non-refundable once prescribed.
Is OneTwenty available in all states?
Site FAQ: 'available in 49 states except for Rhode Island'; NY and NJ carry a higher fee ($749/yr) because of state lab-draw rules. DC not mentioned.
Does OneTwenty include lab work?
Included in the programme price.
Sources
Regulatory and primary sources
- OneTwenty homepage and FAQ ↗ · supports: url, labsIncluded, insurance, statesServed, statesDetail, priceFrom, priceDetail, costPublished, stillOperating
- OneTwenty Payment and Refund Policy (updated July 28, 2026) ↗ · supports: cancellation, cancellationDetail, priceDetail, labsIncluded
- OneTwenty Longevity Treatments ↗ · supports: medications, fdaBarredOffered, priceFrom, prescriberModel
- OneTwenty Press (closed beta announcements) ↗ · supports: stillOperating, notes
- OneTwenty Terms of Service ↗ · supports: notes
- Trustpilot (404, no profile) ↗ · supports: ratings
- Lindy Health clinic scoring rubric ↗ · the six criteria, their weights and the scoring tables