OneTwenty at a glance
What OneTwenty looks like
How much does OneTwenty cost?
From $499/yr membership ($749/yr in NY/NJ); medications $49 to $279/mo extra. Pricing page (seen 2026-11-05; the page says its prices were checked on 2 November 2026): $499 a year, billed annually, for four lab panels: a 101-marker baseline (OneTwenty's own count) plus three follow-up panels of 20 to 40 markers, one every 90 days ('161 to 221 lab results a year'). Walk-in draws at Quest are included; an at-home draw is $99 per draw. NY and NJ: $749 a year because Quest cannot be used there. Add-ons: custom supplement packs from $45/mo; extra lab panels 'at cost' (no prices listed). Medications are priced per product on each treatment page: metformin and sildenafil $49/mo, tadalafil $79/mo, GHK-Cu cream and testosterone cypionate $99/mo, enclomiphene, glutathione (injection or nasal) and oxytocin $129/mo, sermorelin and NAD+ (injection or nasal) $149/mo, compounded semaglutide $179/mo, PT-141 $199/mo, tirzepatide $279/mo or $749 billed quarterly. Whether a separate provider consultation fee applies is not stated. The 'Founding pricing ends at public launch' line seen on 2026-10-17 no longer appears on the homepage or pricing page, but the What We Test page still says 'Now accepting founding members'.
Price transparency on our rubric: Full price published before checkout. Prices were checked on November 5, 2026 and change often; confirm at checkout.
OneTwenty pros and cons
Pros
- Four lab panels a year (101-marker baseline plus three 20 to 40 marker follow-ups) are included in the membership price
- Membership and every available medication have a published monthly price: $499/yr ($749/yr in NY/NJ), medications $49 to $279/mo
- Lists 49 states (all but Rhode Island)
Cons
- The annual membership is non-refundable after a 7-day window, and only if no service has started (3% fee applies)
- Not a medical practice: prescriptions come from unnamed third-party telehealth providers, and the site does not say whether they are physicians or NPs or whether visits are by video
- Early-stage company: it opened a closed beta of 25 founding members in December 2025 and still advertises founding membership
- No direct insurance billing (HSA/FSA reimbursement only)
How OneTwenty scores
OneTwenty scores 9.9 out of 10 on the five criteria every clinic is scored on.
n/a = not applicable to this kind of provider · ? = not verifiable from published pages. How each criterion is scored.
What OneTwenty prescribes
- Enclomiphene
- Compounded semaglutide
- Tirzepatide
- Sermorelin
- Sildenafil
- Tadalafil
- PT-141 (bremelanotide)
- Oxytocin nasal spray
- Metformin
- NAD+ (injection and nasal spray)
- Glutathione (injection and nasal spray)
- GHK-Cu cream
- Testosterone cypionate
In our compound directory: Semaglutide, Tirzepatide, Sermorelin, Tesamorelin, Gonadorelin.
How to cancel OneTwenty
Self-serve online. Payment and Refund Policy (updated 2026-07-28): cancel via the option in account settings or by emailing support@onetwenty.com. The annual membership renews automatically. A refund is available only within 7 days of purchase and only if no service has started, minus a 3% fee. After that the annual fee is non-refundable, except for a discretionary prorated refund if no lab is reachable. Medication add-ons are non-refundable once prescribed.
Is OneTwenty available in my state?
49 states. Site FAQ: 'available in 49 states except for Rhode Island'; NY and NJ carry a higher fee ($749/yr) because of state lab-draw rules. DC not mentioned.
Regulatory and legal history
We found no FDA warning letters, FTC actions, state board actions or class actions against OneTwenty in our search on November 5, 2026. That is not proof that none exist.
Who OneTwenty is best for
People who want their blood retested every 90 days (a 101-marker baseline plus three follow-up panels a year) and want custom supplements and prescriptions, at published prices, driven by those results in one membership.
Highest-scoring alternatives for bloodwork & longevity: InsideTracker (10.0), Quest Health (9.9), Function Health (9.8), Superpower (9.6).
OneTwenty FAQ
How much does OneTwenty cost?
OneTwenty starts at $499/yr membership ($749/yr in NY/NJ); medications $49 to $279/mo extra. Pricing page (seen 2026-11-05; the page says its prices were checked on 2 November 2026): $499 a year, billed annually, for four lab panels: a 101-marker baseline (OneTwenty's own count) plus three follow-up panels of 20 to 40 markers, one every 90 days ('161 to 221 lab results a year'). Walk-in draws at Quest are included; an at-home draw is $99 per draw. NY and NJ: $749 a year because Quest cannot be used there. Add-ons: custom supplement packs from $45/mo; extra lab panels 'at cost' (no prices listed). Medications are priced per product on each treatment page: metformin and sildenafil $49/mo, tadalafil $79/mo, GHK-Cu cream and testosterone cypionate $99/mo, enclomiphene, glutathione (injection or nasal) and oxytocin $129/mo, sermorelin and NAD+ (injection or nasal) $149/mo, compounded semaglutide $179/mo, PT-141 $199/mo, tirzepatide $279/mo or $749 billed quarterly. Whether a separate provider consultation fee applies is not stated. The 'Founding pricing ends at public launch' line seen on 2026-10-17 no longer appears on the homepage or pricing page, but the What We Test page still says 'Now accepting founding members'.
Does OneTwenty take insurance?
No. OneTwenty is cash pay. Some patients use their own insurance at an outside pharmacy for branded medication.
Is OneTwenty legit?
OneTwenty is an operating US telehealth provider. We found no regulatory actions in our search.
How do I cancel OneTwenty?
Payment and Refund Policy (updated 2026-07-28): cancel via the option in account settings or by emailing support@onetwenty.com. The annual membership renews automatically. A refund is available only within 7 days of purchase and only if no service has started, minus a 3% fee. After that the annual fee is non-refundable, except for a discretionary prorated refund if no lab is reachable. Medication add-ons are non-refundable once prescribed.
Is OneTwenty available in all states?
Site FAQ: 'available in 49 states except for Rhode Island'; NY and NJ carry a higher fee ($749/yr) because of state lab-draw rules. DC not mentioned.
Does OneTwenty include lab work?
Included in the programme price.
Sources
Regulatory and primary sources
- OneTwenty homepage and FAQ ↗ · supports: url, labsIncluded, insurance, statesServed, statesDetail, priceFrom, costPublished, stillOperating
- OneTwenty Pricing (prices checked by the company 2026-11-02; seen 2026-11-05) ↗ · supports: priceFrom, priceDetail, costPublished, statesServed, statesDetail, cancellation, labsIncluded
- OneTwenty Payment and Refund Policy (updated July 28, 2026) ↗ · supports: cancellation, cancellationDetail, priceDetail, labsIncluded
- OneTwenty Longevity Treatments ↗ · supports: medications, fdaBarredOffered, priceFrom, prescriberModel, notes
- OneTwenty Tirzepatide ($279/mo or $749 quarterly) ↗ · supports: priceDetail, costPublished
- OneTwenty Testosterone Cypionate ($99/mo) ↗ · supports: medications, priceDetail
- OneTwenty BPC-157 (coming soon) ↗ · supports: notes, fdaBarredOffered
- OneTwenty What We Test (101-marker baseline; 'Now accepting founding members') ↗ · supports: priceDetail, cons
- OneTwenty Press (closed beta announcements) ↗ · supports: stillOperating, notes
- OneTwenty Terms of Service (effective August 27, 2026) ↗ · supports: notes, prescriberModel
- OneTwenty Privacy Policy (effective August 27, 2026) ↗ · supports: notes
- Upwork: Physician Advisor (MD/DO), Preventive & Longevity Medicine (search snippet; page returned 403) ↗ · supports: notes, prescriberModel
- AJMC: 5 things to know about HHS's interim peptide compounding policy (2026-10-29) ↗ · supports: notes, fdaBarredOffered
- Trustpilot (404, no profile; rechecked 2026-11-05) ↗ · supports: ratings
- Lindy Health clinic scoring rubric ↗ · the five criteria, their weights and the scoring tables