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Clinics · Comparison

OneTwenty vs Rythm Health

Both are primarily bloodwork & longevity providers, so the differences are in consult model, what is bundled, who prescribes, and price.

OneTwenty logo OneTwenty From $499/yr membership Read the OneTwenty review →
vs
Rythm Health logo Rythm Health From $79/month Read the Rythm Health review →

Side-by-side comparison

OneTwenty logoOneTwentyRythm Health logoRythm Health
Our score9.9 / 109.1 / 10
Starting price$499/yr membership$79/month
Primary serviceBloodwork & longevityBloodwork & longevity
All servicesBloodwork, TRT, GLP-1, PeptidesBloodwork
Consult modelUnconfirmedUnconfirmed
PrescriberUnconfirmedUnconfirmed
LabsIncludedIncluded
InsuranceCash payCash pay
Availability49 states50 states
CancellationSelf-serve onlineSelf-serve online
Trustpilot—4.8 / 5 (3,440 reviews)
Regulatory / legal recordNone foundNone found
Visit ↗Visit ↗

* Provisional score: one or two criteria could not be verified.

Which one is right for you

Choose OneTwenty if…

People who want their blood retested every 90 days (a 101-marker baseline plus three follow-up panels a year) and want custom supplements and prescriptions, at published prices, driven by those results in one membership.

  • Four lab panels a year (101-marker baseline plus three 20 to 40 marker follow-ups) are included in the membership price
  • Membership and every available medication have a published monthly price: $499/yr ($749/yr in NY/NJ), medications $49 to $279/mo
  • Lists 49 states (all but Rhode Island)

Choose Rythm Health if…

People who want to track a short set of hormone, lipid and metabolic markers every month or two from home, and who will take results to their own doctor for any treatment.

  • Published per-kit price of $79 for repeat testing, with the option to skip up to 90 days between kits
  • Home collection with the Tasso+ device; no lab visit or phlebotomist
  • Self-serve cancellation from the account dashboard

Price: what you actually pay

OneTwenty

Pricing page (seen 2026-11-05; the page says its prices were checked on 2 November 2026): $499 a year, billed annually, for four lab panels: a 101-marker baseline (OneTwenty's own count) plus three follow-up panels of 20 to 40 markers, one every 90 days ('161 to 221 lab results a year'). Walk-in draws at Quest are included; an at-home draw is $99 per draw. NY and NJ: $749 a year because Quest cannot be used there. Add-ons: custom supplement packs from $45/mo; extra lab panels 'at cost' (no prices listed). Medications are priced per product on each treatment page: metformin and sildenafil $49/mo, tadalafil $79/mo, GHK-Cu cream and testosterone cypionate $99/mo, enclomiphene, glutathione (injection or nasal) and oxytocin $129/mo, sermorelin and NAD+ (injection or nasal) $149/mo, compounded semaglutide $179/mo, PT-141 $199/mo, tirzepatide $279/mo or $749 billed quarterly. Whether a separate provider consultation fee applies is not stated. The 'Founding pricing ends at public launch' line seen on 2026-10-17 no longer appears on the homepage or pricing page, but the What We Test page still says 'Now accepting founding members'.

Rythm Health

Homepage (seen 2026-11-05): '$79/test', billed as a monthly subscription; first kit 30% off at $55.30 under a 'limited time' offer; '+ shipping & tax' with the shipping amount not shown before checkout. Each kit tests 25+ biomarkers (separate men's and women's panels: hormones including total and free testosterone, estradiol, SHBG, cortisol; TSH; ApoB, lipids, hsCRP; vitamin D, ferritin, fructosamine; kidney and liver markers) from a capillary sample collected at home with the Tasso+ device. Membership includes the kit, lab analysis, results dashboard and an AI coach. Members can skip up to 90 days at a time without charge. HSA/FSA eligible.

What happens after you sign up

OneTwenty

Treatments offered: Enclomiphene, Compounded semaglutide, Tirzepatide, Sermorelin, Sildenafil, Tadalafil, PT-141 (bremelanotide), Oxytocin nasal spray, Metformin, NAD+ (injection and nasal spray), Glutathione (injection and nasal spray), GHK-Cu cream, Testosterone cypionate.

Rythm Health

Testing and insights only. No prescriptions.

Cancelling and refunds

OneTwenty

Payment and Refund Policy (updated 2026-07-28): cancel via the option in account settings or by emailing support@onetwenty.com. The annual membership renews automatically. A refund is available only within 7 days of purchase and only if no service has started, minus a 3% fee. After that the annual fee is non-refundable, except for a discretionary prorated refund if no lab is reachable. Medication add-ons are non-refundable once prescribed.

Rythm Health

FAQ: cancel in the account under Accounts > Billing > 'Cancel Subscription'; results stay accessible but the AI coach ends. Refund and Skip Policy (updated 2025-02-11): cancel via dashboard > account billing > 'Manage Shipping and Payment'; cancellation does not trigger a refund. A '90-day money-back guarantee' applies to the first test only, and only if the sample was collected and returned to the lab and the request is made within 7 days of receiving results. The latest monthly charge can be reversed only if the kit has not yet been prepared to ship. Used kits are not refundable and shipping costs are non-refundable. Terms s.11.2: subscriptions renew automatically each billing period until cancelled.

Where each is available

OneTwenty

Site FAQ: 'available in 49 states except for Rhode Island'; NY and NJ carry a higher fee ($749/yr) because of state lab-draw rules. DC not mentioned.

Rythm Health

FAQ: 'Rythm is currently available nationwide across all 50 U.S. states.' Requires a U.S. shipping address FedEx can deliver to and collect from; no international shipping. DC is not mentioned. Footer lists the lab as 'CLEP Permitted' (New York's lab permit program).

Full breakdown of each

#1 OneTwenty logo

People who want their blood retested every 90 days (a 101-marker baseline plus three follow-up panels a year) and want custom supplements and prescriptions, at published prices, driven by those results in one membership.

Starting price
$499/yr membership
Consult model
Unconfirmed
Prescriber
Unconfirmed
Labs
Included
Insurance
Cash pay
Availability
49 states
Cancellation
Self-serve online
Founded
Unconfirmed

Pricing

Pricing page (seen 2026-11-05; the page says its prices were checked on 2 November 2026): $499 a year, billed annually, for four lab panels: a 101-marker baseline (OneTwenty's own count) plus three follow-up panels of 20 to 40 markers, one every 90 days ('161 to 221 lab results a year'). Walk-in draws at Quest are included; an at-home draw is $99 per draw. NY and NJ: $749 a year because Quest cannot be used there. Add-ons: custom supplement packs from $45/mo; extra lab panels 'at cost' (no prices listed). Medications are priced per product on each treatment page: metformin and sildenafil $49/mo, tadalafil $79/mo, GHK-Cu cream and testosterone cypionate $99/mo, enclomiphene, glutathione (injection or nasal) and oxytocin $129/mo, sermorelin and NAD+ (injection or nasal) $149/mo, compounded semaglutide $179/mo, PT-141 $199/mo, tirzepatide $279/mo or $749 billed quarterly. Whether a separate provider consultation fee applies is not stated. The 'Founding pricing ends at public launch' line seen on 2026-10-17 no longer appears on the homepage or pricing page, but the What We Test page still says 'Now accepting founding members'.

Prices as listed on November 5, 2026. They change often; confirm at checkout.

What we like

  • Four lab panels a year (101-marker baseline plus three 20 to 40 marker follow-ups) are included in the membership price
  • Membership and every available medication have a published monthly price: $499/yr ($749/yr in NY/NJ), medications $49 to $279/mo
  • Lists 49 states (all but Rhode Island)

Watch out for

  • The annual membership is non-refundable after a 7-day window, and only if no service has started (3% fee applies)
  • Not a medical practice: prescriptions come from unnamed third-party telehealth providers, and the site does not say whether they are physicians or NPs or whether visits are by video
  • Early-stage company: it opened a closed beta of 25 founding members in December 2025 and still advertises founding membership
  • No direct insurance billing (HSA/FSA reimbursement only)
Treatments offered
EnclomipheneCompounded semaglutideTirzepatideSermorelinSildenafilTadalafilPT-141 (bremelanotide)Oxytocin nasal sprayMetforminNAD+ (injection and nasal spray)Glutathione (injection and nasal spray)GHK-Cu creamTestosterone cypionate
Cancelling

Payment and Refund Policy (updated 2026-07-28): cancel via the option in account settings or by emailing support@onetwenty.com. The annual membership renews automatically. A refund is available only within 7 days of purchase and only if no service has started, minus a 3% fee. After that the annual fee is non-refundable, except for a discretionary prorated refund if no lab is reachable. Medication add-ons are non-refundable once prescribed.

Where it is available

Site FAQ: 'available in 49 states except for Rhode Island'; NY and NJ carry a higher fee ($749/yr) because of state lab-draw rules. DC not mentioned.

#2 Rythm Health logo

People who want to track a short set of hormone, lipid and metabolic markers every month or two from home, and who will take results to their own doctor for any treatment.

Starting price
$79/month
Consult model
Unconfirmed
Prescriber
Unconfirmed
Labs
Included
Insurance
Cash pay
Availability
50 states
Cancellation
Self-serve online
Founded
Unconfirmed

Pricing

Homepage (seen 2026-11-05): '$79/test', billed as a monthly subscription; first kit 30% off at $55.30 under a 'limited time' offer; '+ shipping & tax' with the shipping amount not shown before checkout. Each kit tests 25+ biomarkers (separate men's and women's panels: hormones including total and free testosterone, estradiol, SHBG, cortisol; TSH; ApoB, lipids, hsCRP; vitamin D, ferritin, fructosamine; kidney and liver markers) from a capillary sample collected at home with the Tasso+ device. Membership includes the kit, lab analysis, results dashboard and an AI coach. Members can skip up to 90 days at a time without charge. HSA/FSA eligible.

Prices as listed on November 5, 2026. They change often; confirm at checkout.

What we like

  • Published per-kit price of $79 for repeat testing, with the option to skip up to 90 days between kits
  • Home collection with the Tasso+ device; no lab visit or phlebotomist
  • Self-serve cancellation from the account dashboard
  • Runs its own CLIA-certified, CAP-accredited lab and states availability in all 50 states

Watch out for

  • Panel is small (25+ markers) and differs by sex because of sample volume limits; some markers are dropped if the sample is short or outside stability windows
  • Shipping is charged on top of the $79 price and the amount is not shown before checkout
  • Money-back guarantee covers the first test only and requires a request within 7 days of results
  • No clinician consultation, diagnosis or prescribing; interpretation comes from an AI coach
Cancelling

FAQ: cancel in the account under Accounts > Billing > 'Cancel Subscription'; results stay accessible but the AI coach ends. Refund and Skip Policy (updated 2025-02-11): cancel via dashboard > account billing > 'Manage Shipping and Payment'; cancellation does not trigger a refund. A '90-day money-back guarantee' applies to the first test only, and only if the sample was collected and returned to the lab and the request is made within 7 days of receiving results. The latest monthly charge can be reversed only if the kit has not yet been prepared to ship. Used kits are not refundable and shipping costs are non-refundable. Terms s.11.2: subscriptions renew automatically each billing period until cancelled.

Where it is available

FAQ: 'Rythm is currently available nationwide across all 50 U.S. states.' Requires a U.S. shipping address FedEx can deliver to and collect from; no international shipping. DC is not mentioned. Footer lists the lab as 'CLEP Permitted' (New York's lab permit program).

OneTwenty vs Rythm Health: common questions

Is OneTwenty or Rythm Health better?

OneTwenty ranks higher on our rubric (9.9 vs 9.1 out of 10; * means provisional, and fully verified scores rank first). That reflects price transparency, labs, availability, cancellation terms and treatment range, not clinical outcomes. OneTwenty: People who want their blood retested every 90 days (a 101-marker baseline plus three follow-up panels a year) and want custom supplements and prescriptions, at published prices, driven by those results in one membership. Rythm Health: People who want to track a short set of hormone, lipid and metabolic markers every month or two from home, and who will take results to their own doctor for any treatment.

Which is cheaper, OneTwenty or Rythm Health?

OneTwenty starts at $499/yr membership ($749/yr in NY/NJ); medications $49 to $279/mo extra. Rythm Health starts at $79/month (one at-home test kit per month, plus shipping and tax). Compare what each price includes, especially labs and medication.

Do OneTwenty and Rythm Health include lab work?

OneTwenty: included. Rythm Health: included.

Which is easier to cancel?

OneTwenty: Payment and Refund Policy (updated 2026-07-28): cancel via the option in account settings or by emailing support@onetwenty.com. The annual membership renews automatically. A refund is available only within 7 days of purchase and only if no service has started, minus a 3% fee. After that the annual fee is non-refundable, except for a discretionary prorated refund if no lab is reachable. Medication add-ons are non-refundable once prescribed. Rythm Health: FAQ: cancel in the account under Accounts > Billing > 'Cancel Subscription'; results stay accessible but the AI coach ends. Refund and Skip Policy (updated 2025-02-11): cancel via dashboard > account billing > 'Manage Shipping and Payment'; cancellation does not trigger a refund. A '90-day money-back guarantee' applies to the first test only, and only if the sample was collected and returned to the lab and the request is made within 7 days of receiving results. The latest monthly charge can be reversed only if the kit has not yet been prepared to ship. Used kits are not refundable and shipping costs are non-refundable. Terms s.11.2: subscriptions renew automatically each billing period until cancelled.

Can OneTwenty or Rythm Health prescribe treatment?

OneTwenty: yes (Enclomiphene, Compounded semaglutide, Tirzepatide, Sermorelin). Rythm Health: no, testing and insights only.

Which is available in more states?

OneTwenty: 49 states. Rythm Health: 50 states.

Sources

Regulatory and primary sources

  1. OneTwenty: OneTwenty homepage and FAQ ↗
  2. OneTwenty: OneTwenty Pricing (prices checked by the company 2026-11-02; seen 2026-11-05) ↗
  3. OneTwenty: OneTwenty Payment and Refund Policy (updated July 28, 2026) ↗
  4. OneTwenty: OneTwenty Longevity Treatments ↗
  5. OneTwenty: OneTwenty Tirzepatide ($279/mo or $749 quarterly) ↗
  6. OneTwenty: OneTwenty Testosterone Cypionate ($99/mo) ↗
  7. OneTwenty: OneTwenty BPC-157 (coming soon) ↗
  8. OneTwenty: OneTwenty What We Test (101-marker baseline; 'Now accepting founding members') ↗
  9. OneTwenty: OneTwenty Press (closed beta announcements) ↗
  10. OneTwenty: OneTwenty Terms of Service (effective August 27, 2026) ↗
  11. OneTwenty: OneTwenty Privacy Policy (effective August 27, 2026) ↗
  12. OneTwenty: Upwork: Physician Advisor (MD/DO), Preventive & Longevity Medicine (search snippet; page returned 403) ↗
  13. OneTwenty: AJMC: 5 things to know about HHS's interim peptide compounding policy (2026-10-29) ↗
  14. OneTwenty: Trustpilot (404, no profile; rechecked 2026-11-05) ↗
  15. Rythm Health: Rythm homepage ↗
  16. Rythm Health: Rythm FAQs ↗
  17. Rythm Health: Rythm Refund and Skip Policy (updated 2025-02-11) ↗
  18. Rythm Health: Rythm Terms and Conditions ↗
  19. Rythm Health: Rythm: What we test ↗
  20. Rythm Health: Laboratory Technician job listing, Omaha NE (search result) ↗
  21. Rythm Health: Rythm Health on Trustpilot ↗
  22. Lindy Health clinic scoring rubric ↗