Search ↗

Clinics · Comparison

OneTwenty vs Superpower

Both are primarily bloodwork & longevity providers, so the differences are in consult model, what is bundled, who prescribes, and price.

OneTwenty logo OneTwenty From $499/yr membership Read the OneTwenty review →
vs
Superpower logo Superpower From $199/yr Read the Superpower review →

Side-by-side comparison

OneTwenty logoOneTwentySuperpower logoSuperpower
Our score9.9 / 109.6 / 10
Starting price$499/yr membership$199/yr
Primary serviceBloodwork & longevityBloodwork & longevity
All servicesBloodwork, TRT, GLP-1, PeptidesBloodwork
Consult modelUnconfirmedAsynchronous (questionnaire + messaging)
PrescriberUnconfirmedMD/DO + NP/PA
LabsIncludedIncluded
InsuranceCash payCash pay
Availability49 states42 states
CancellationSelf-serve onlineSelf-serve online
Trustpilot—4.4 / 5 (343 reviews)
Regulatory / legal recordNone foundFunction Health, Inc. v. Superpower Health, Inc., No. 2:26-cv-00810 (C.D. Cal., filed 2026-01-26): false-advertising and unfair-competition suit over Superpower's '100+ biomarkers' and comparative claims
Visit ↗Visit ↗

* Provisional score: one or two criteria could not be verified.

Which one is right for you

Choose OneTwenty if…

People who want their blood retested every 90 days (a 101-marker baseline plus three follow-up panels a year) and want custom supplements and prescriptions, at published prices, driven by those results in one membership.

  • Four lab panels a year (101-marker baseline plus three 20 to 40 marker follow-ups) are included in the membership price
  • Membership and every available medication have a published monthly price: $499/yr ($749/yr in NY/NJ), medications $49 to $279/mo
  • Lists 49 states (all but Rhode Island)

Choose Superpower if…

Cost-conscious adults wanting an annual baseline lab panel plus optional access to prescriptions through the same app, and who accept that medication prices are not published.

  • Lowest published entry price of the three bloodwork services reviewed ($199/yr with one lab panel)
  • Clinician team includes physicians and nurse practitioners and can prescribe
  • Self-serve cancellation in account or by email

Price: what you actually pay

OneTwenty

Pricing page (seen 2026-11-05; the page says its prices were checked on 2 November 2026): $499 a year, billed annually, for four lab panels: a 101-marker baseline (OneTwenty's own count) plus three follow-up panels of 20 to 40 markers, one every 90 days ('161 to 221 lab results a year'). Walk-in draws at Quest are included; an at-home draw is $99 per draw. NY and NJ: $749 a year because Quest cannot be used there. Add-ons: custom supplement packs from $45/mo; extra lab panels 'at cost' (no prices listed). Medications are priced per product on each treatment page: metformin and sildenafil $49/mo, tadalafil $79/mo, GHK-Cu cream and testosterone cypionate $99/mo, enclomiphene, glutathione (injection or nasal) and oxytocin $129/mo, sermorelin and NAD+ (injection or nasal) $149/mo, compounded semaglutide $179/mo, PT-141 $199/mo, tirzepatide $279/mo or $749 billed quarterly. Whether a separate provider consultation fee applies is not stated. The 'Founding pricing ends at public launch' line seen on 2026-10-17 no longer appears on the homepage or pricing page, but the What We Test page still says 'Now accepting founding members'.

Superpower

Homepage (seen 2026-11-05): 'Starts at $199/year' ('$0.55/day'); includes one comprehensive blood draw per year, which Superpower describes as '100+ biomarkers' (its own comparison pages count 103: 57 distinct and 46 calculated), biological age and health scores, action plan, AI and on-demand care team. New members are offered a complimentary follow-up test (stated value $99). An at-home draw is $119 extra. Follow-up tests, add-on tests and prescriptions are priced separately; the homepage says 'Pricing may vary for members in New York and New Jersey' and the comparison pages state +$200 there ($399/yr). Peptides page (seen 2026-11-05): BPC-157 and TB-500 $149/mo, MOTS-c $199/mo, taken as paid pre-orders with a target ship date of late November 2026; the peptide plan includes a 40+ biomarker blood test and membership.

What happens after you sign up

OneTwenty

Treatments offered: Enclomiphene, Compounded semaglutide, Tirzepatide, Sermorelin, Sildenafil, Tadalafil, PT-141 (bremelanotide), Oxytocin nasal spray, Metformin, NAD+ (injection and nasal spray), Glutathione (injection and nasal spray), GHK-Cu cream, Testosterone cypionate.

Superpower

Treatments offered: Compounded hormones (unspecified), Compounded peptides (unspecified), GLP-1 medications (agents not named), Sermorelin (per Business Insider report), Tesamorelin (per Business Insider report), SS-31 (per Business Insider report), BPC-157 (pre-order, target ship late November 2026), TB-500 (pre-order, target ship late November 2026), MOTS-c (pre-order, target ship late November 2026). Prescribers: MD/DO + NP/PA.

Cancelling and refunds

OneTwenty

Payment and Refund Policy (updated 2026-07-28): cancel via the option in account settings or by emailing support@onetwenty.com. The annual membership renews automatically. A refund is available only within 7 days of purchase and only if no service has started, minus a 3% fee. After that the annual fee is non-refundable, except for a discretionary prorated refund if no lab is reachable. Medication add-ons are non-refundable once prescribed.

Superpower

Membership Agreement (Last Updated and Effective 9.15.2026) s.14: cancel any time, including during the initial term, via the cancellation flow in the user account or by emailing concierge@superpower.com; cancellation takes effect on receipt and stops the next renewal, with no cancellation fee. Auto-renews at the then-current non-promotional rate. Homepage: membership stays active through the end of the paid year. s.14(a) offers a one-time 100% refund of the initial-term base fee if requested by the earlier of 7 days after results delivery or 45 days after start, but the FAQ says 'Superpower does not offer refunds at this time.' Prescription products are not refundable.

Where each is available

OneTwenty

Site FAQ: 'available in 49 states except for Rhode Island'; NY and NJ carry a higher fee ($749/yr) because of state lab-draw rules. DC not mentioned.

Superpower

41 states + DC. FAQ and comparison page: not yet available in AK, AR, HI, LA, MS, ND, RI, SD, WY. FAQ: 'Superpower can write a prescription in all states where we're live, except Alabama and West Virginia'; the peptides page says the same for peptide shipping. NY/NJ membership is $200 higher.

Full breakdown of each

#1 OneTwenty logo

People who want their blood retested every 90 days (a 101-marker baseline plus three follow-up panels a year) and want custom supplements and prescriptions, at published prices, driven by those results in one membership.

Starting price
$499/yr membership
Consult model
Unconfirmed
Prescriber
Unconfirmed
Labs
Included
Insurance
Cash pay
Availability
49 states
Cancellation
Self-serve online
Founded
Unconfirmed

Pricing

Pricing page (seen 2026-11-05; the page says its prices were checked on 2 November 2026): $499 a year, billed annually, for four lab panels: a 101-marker baseline (OneTwenty's own count) plus three follow-up panels of 20 to 40 markers, one every 90 days ('161 to 221 lab results a year'). Walk-in draws at Quest are included; an at-home draw is $99 per draw. NY and NJ: $749 a year because Quest cannot be used there. Add-ons: custom supplement packs from $45/mo; extra lab panels 'at cost' (no prices listed). Medications are priced per product on each treatment page: metformin and sildenafil $49/mo, tadalafil $79/mo, GHK-Cu cream and testosterone cypionate $99/mo, enclomiphene, glutathione (injection or nasal) and oxytocin $129/mo, sermorelin and NAD+ (injection or nasal) $149/mo, compounded semaglutide $179/mo, PT-141 $199/mo, tirzepatide $279/mo or $749 billed quarterly. Whether a separate provider consultation fee applies is not stated. The 'Founding pricing ends at public launch' line seen on 2026-10-17 no longer appears on the homepage or pricing page, but the What We Test page still says 'Now accepting founding members'.

Prices as listed on November 5, 2026. They change often; confirm at checkout.

What we like

  • Four lab panels a year (101-marker baseline plus three 20 to 40 marker follow-ups) are included in the membership price
  • Membership and every available medication have a published monthly price: $499/yr ($749/yr in NY/NJ), medications $49 to $279/mo
  • Lists 49 states (all but Rhode Island)

Watch out for

  • The annual membership is non-refundable after a 7-day window, and only if no service has started (3% fee applies)
  • Not a medical practice: prescriptions come from unnamed third-party telehealth providers, and the site does not say whether they are physicians or NPs or whether visits are by video
  • Early-stage company: it opened a closed beta of 25 founding members in December 2025 and still advertises founding membership
  • No direct insurance billing (HSA/FSA reimbursement only)
Treatments offered
EnclomipheneCompounded semaglutideTirzepatideSermorelinSildenafilTadalafilPT-141 (bremelanotide)Oxytocin nasal sprayMetforminNAD+ (injection and nasal spray)Glutathione (injection and nasal spray)GHK-Cu creamTestosterone cypionate
Cancelling

Payment and Refund Policy (updated 2026-07-28): cancel via the option in account settings or by emailing support@onetwenty.com. The annual membership renews automatically. A refund is available only within 7 days of purchase and only if no service has started, minus a 3% fee. After that the annual fee is non-refundable, except for a discretionary prorated refund if no lab is reachable. Medication add-ons are non-refundable once prescribed.

Where it is available

Site FAQ: 'available in 49 states except for Rhode Island'; NY and NJ carry a higher fee ($749/yr) because of state lab-draw rules. DC not mentioned.

#2 Superpower logo

Cost-conscious adults wanting an annual baseline lab panel plus optional access to prescriptions through the same app, and who accept that medication prices are not published.

Starting price
$199/yr
Consult model
Asynchronous (questionnaire + messaging)
Prescriber
MD/DO + NP/PA
Labs
Included
Insurance
Cash pay
Availability
42 states
Cancellation
Self-serve online
Founded
2023

Pricing

Homepage (seen 2026-11-05): 'Starts at $199/year' ('$0.55/day'); includes one comprehensive blood draw per year, which Superpower describes as '100+ biomarkers' (its own comparison pages count 103: 57 distinct and 46 calculated), biological age and health scores, action plan, AI and on-demand care team. New members are offered a complimentary follow-up test (stated value $99). An at-home draw is $119 extra. Follow-up tests, add-on tests and prescriptions are priced separately; the homepage says 'Pricing may vary for members in New York and New Jersey' and the comparison pages state +$200 there ($399/yr). Peptides page (seen 2026-11-05): BPC-157 and TB-500 $149/mo, MOTS-c $199/mo, taken as paid pre-orders with a target ship date of late November 2026; the peptide plan includes a 40+ biomarker blood test and membership.

Prices as listed on November 5, 2026. They change often; confirm at checkout.

What we like

  • Lowest published entry price of the three bloodwork services reviewed ($199/yr with one lab panel)
  • Clinician team includes physicians and nurse practitioners and can prescribe
  • Self-serve cancellation in account or by email
  • HSA/FSA eligible

Watch out for

  • Only one blood test per year included; follow-up testing costs extra (one complimentary follow-up offered to new members)
  • Not available in 9 states (AK, AR, HI, LA, MS, ND, RI, SD, WY); no prescribing in AL or WV; NY/NJ priced at $399/yr
  • Most prescription prices are not listed publicly; only the pre-order peptides show prices
  • Sells pre-orders for BPC-157, TB-500 and MOTS-c, unapproved peptides compounded under a 2026 HHS enforcement discretion policy, before they ship
Treatments offered
Compounded hormones (unspecified)Compounded peptides (unspecified)GLP-1 medications (agents not named)Sermorelin (per Business Insider report)Tesamorelin (per Business Insider report)SS-31 (per Business Insider report)BPC-157 (pre-order, target ship late November 2026)TB-500 (pre-order, target ship late November 2026)MOTS-c (pre-order, target ship late November 2026)
Cancelling

Membership Agreement (Last Updated and Effective 9.15.2026) s.14: cancel any time, including during the initial term, via the cancellation flow in the user account or by emailing concierge@superpower.com; cancellation takes effect on receipt and stops the next renewal, with no cancellation fee. Auto-renews at the then-current non-promotional rate. Homepage: membership stays active through the end of the paid year. s.14(a) offers a one-time 100% refund of the initial-term base fee if requested by the earlier of 7 days after results delivery or 45 days after start, but the FAQ says 'Superpower does not offer refunds at this time.' Prescription products are not refundable.

Where it is available

41 states + DC. FAQ and comparison page: not yet available in AK, AR, HI, LA, MS, ND, RI, SD, WY. FAQ: 'Superpower can write a prescription in all states where we're live, except Alabama and West Virginia'; the peptides page says the same for peptide shipping. NY/NJ membership is $200 higher.

On the public record
  • 2026-01 Function Health, Inc. v. Superpower Health, Inc., No. 2:26-cv-00810 (C.D. Cal., filed 2026-01-26): false-advertising and unfair-competition suit over Superpower's '100+ biomarkers' and comparative claims. No ruling, settlement or dismissal found as of 2026-11-05. Source ↗

OneTwenty vs Superpower: common questions

Is OneTwenty or Superpower better?

OneTwenty ranks higher on our rubric (9.9 vs 9.6 out of 10; * means provisional, and fully verified scores rank first). That reflects price transparency, labs, availability, cancellation terms and treatment range, not clinical outcomes. OneTwenty: People who want their blood retested every 90 days (a 101-marker baseline plus three follow-up panels a year) and want custom supplements and prescriptions, at published prices, driven by those results in one membership. Superpower: Cost-conscious adults wanting an annual baseline lab panel plus optional access to prescriptions through the same app, and who accept that medication prices are not published.

Which is cheaper, OneTwenty or Superpower?

OneTwenty starts at $499/yr membership ($749/yr in NY/NJ); medications $49 to $279/mo extra. Superpower starts at $199/yr (one lab panel included; $399/yr in NY/NJ). Compare what each price includes, especially labs and medication.

Do OneTwenty and Superpower include lab work?

OneTwenty: included. Superpower: included.

Which is easier to cancel?

OneTwenty: Payment and Refund Policy (updated 2026-07-28): cancel via the option in account settings or by emailing support@onetwenty.com. The annual membership renews automatically. A refund is available only within 7 days of purchase and only if no service has started, minus a 3% fee. After that the annual fee is non-refundable, except for a discretionary prorated refund if no lab is reachable. Medication add-ons are non-refundable once prescribed. Superpower: Membership Agreement (Last Updated and Effective 9.15.2026) s.14: cancel any time, including during the initial term, via the cancellation flow in the user account or by emailing concierge@superpower.com; cancellation takes effect on receipt and stops the next renewal, with no cancellation fee. Auto-renews at the then-current non-promotional rate. Homepage: membership stays active through the end of the paid year. s.14(a) offers a one-time 100% refund of the initial-term base fee if requested by the earlier of 7 days after results delivery or 45 days after start, but the FAQ says 'Superpower does not offer refunds at this time.' Prescription products are not refundable.

Can OneTwenty or Superpower prescribe treatment?

OneTwenty: yes (Enclomiphene, Compounded semaglutide, Tirzepatide, Sermorelin). Superpower: yes (Compounded hormones (unspecified), Compounded peptides (unspecified), GLP-1 medications (agents not named), Sermorelin (per Business Insider report)).

Which is available in more states?

OneTwenty: 49 states. Superpower: 42 states.

Sources

Regulatory and primary sources

  1. OneTwenty: OneTwenty homepage and FAQ ↗
  2. OneTwenty: OneTwenty Pricing (prices checked by the company 2026-11-02; seen 2026-11-05) ↗
  3. OneTwenty: OneTwenty Payment and Refund Policy (updated July 28, 2026) ↗
  4. OneTwenty: OneTwenty Longevity Treatments ↗
  5. OneTwenty: OneTwenty Tirzepatide ($279/mo or $749 quarterly) ↗
  6. OneTwenty: OneTwenty Testosterone Cypionate ($99/mo) ↗
  7. OneTwenty: OneTwenty BPC-157 (coming soon) ↗
  8. OneTwenty: OneTwenty What We Test (101-marker baseline; 'Now accepting founding members') ↗
  9. OneTwenty: OneTwenty Press (closed beta announcements) ↗
  10. OneTwenty: OneTwenty Terms of Service (effective August 27, 2026) ↗
  11. OneTwenty: OneTwenty Privacy Policy (effective August 27, 2026) ↗
  12. OneTwenty: Upwork: Physician Advisor (MD/DO), Preventive & Longevity Medicine (search snippet; page returned 403) ↗
  13. OneTwenty: AJMC: 5 things to know about HHS's interim peptide compounding policy (2026-10-29) ↗
  14. OneTwenty: Trustpilot (404, no profile; rechecked 2026-11-05) ↗
  15. Superpower: Superpower homepage ↗
  16. Superpower: Superpower FAQs ↗
  17. Superpower: Superpower Membership Agreement (Last Updated and Effective 9.15.2026) ↗
  18. Superpower: Superpower vs Hone Health (company comparison page) ↗
  19. Superpower: Superpower wants to make you hotter, smarter, and healthier (Business Insider via AOL; search snippet) ↗
  20. Superpower: Peptides by Superpower (pre-order page, seen 2026-11-05) ↗
  21. Superpower: CB Insights: Superpower ↗
  22. Superpower: Forbes Australia on Superpower founders ↗
  23. Superpower: Function sues Superpower (Athletech News, 2026-02-05) ↗
  24. Superpower: Superpower on Trustpilot ↗
  25. Superpower: Superpower vs OneTwenty (company comparison page; 103-biomarker count, NY/NJ +$200, at-home draw +$119) ↗
  26. Superpower: ArentFox Schiff: Function Health sues Superpower Health (case details; search snippet) ↗
  27. Lindy Health clinic scoring rubric ↗