Health guides · Peptide therapy
The best peptide therapy clinics that prescribe rather than sell
A prescribing clinic can only offer compounds a pharmacy may legally compound, which after the FDA 503A Category 2 decisions excludes BPC-157, ipamorelin and CJC-1295. The clinics here work inside that, which is the point.
Ranked first on the five-criterion rubric, at 9.9/10.
From $499/yr membership Best with labs included
The initial lab panel is inside the published price.
From $125/mo Core care plan Easiest to cancel
No subscription to cancel.
From Under $175/mo average for TRT in year oneQuick comparison
| # | Provider | Score | From | Labs | Prescriber | States | Cancel |
|---|---|---|---|---|---|---|---|
| 1 | OneTwenty | 9.9 | $499/yr membership | Included | — | 49 | Self-serve online |
| 2 | Marek Health | 7.0 | $299 | Extra | MD/DO + NP/PA | 50 | By email or written request |
| 3 | Ways2Well | 6.9 | $125/mo Core care plan | Included | — | 47 | Minimum term or retention process |
| 4 |  Blokes | 6.2 | $99/mo TRT on a 12-month plan | Extra | MD/DO + NP/PA | 34 | Minimum term or retention process |
| 5 | Defy Medical | 6.8* | Under $175/mo average for TRT in year one | Extra | MD/DO + NP/PA | — | No subscription to cancel |
* Provisional: one or two criteria could not be verified from the provider’s published pages and are left out of the average. Provisional scores rank below fully verified ones.
The ranking
OneTwenty
People who want their blood retested every 90 days (a 101-marker baseline plus three follow-up panels a year) and want custom supplements and prescriptions, at published prices, driven by those results in one membership.
- Starting price
- $499/yr membership
- Consult model
- Unconfirmed
- Prescriber
- Unconfirmed
- Labs
- Included
- Insurance
- Cash pay
- Availability
- 49 states
- Cancellation
- Self-serve online
- Founded
- Unconfirmed
Pricing
Pricing page (seen 2026-11-05; the page says its prices were checked on 2 November 2026): $499 a year, billed annually, for four lab panels: a 101-marker baseline (OneTwenty's own count) plus three follow-up panels of 20 to 40 markers, one every 90 days ('161 to 221 lab results a year'). Walk-in draws at Quest are included; an at-home draw is $99 per draw. NY and NJ: $749 a year because Quest cannot be used there. Add-ons: custom supplement packs from $45/mo; extra lab panels 'at cost' (no prices listed). Medications are priced per product on each treatment page: metformin and sildenafil $49/mo, tadalafil $79/mo, GHK-Cu cream and testosterone cypionate $99/mo, enclomiphene, glutathione (injection or nasal) and oxytocin $129/mo, sermorelin and NAD+ (injection or nasal) $149/mo, compounded semaglutide $179/mo, PT-141 $199/mo, tirzepatide $279/mo or $749 billed quarterly. Whether a separate provider consultation fee applies is not stated. The 'Founding pricing ends at public launch' line seen on 2026-10-17 no longer appears on the homepage or pricing page, but the What We Test page still says 'Now accepting founding members'.
Prices as listed on November 5, 2026. They change often; confirm at checkout.
What we like
- Four lab panels a year (101-marker baseline plus three 20 to 40 marker follow-ups) are included in the membership price
- Membership and every available medication have a published monthly price: $499/yr ($749/yr in NY/NJ), medications $49 to $279/mo
- Lists 49 states (all but Rhode Island)
Watch out for
- The annual membership is non-refundable after a 7-day window, and only if no service has started (3% fee applies)
- Not a medical practice: prescriptions come from unnamed third-party telehealth providers, and the site does not say whether they are physicians or NPs or whether visits are by video
- Early-stage company: it opened a closed beta of 25 founding members in December 2025 and still advertises founding membership
- No direct insurance billing (HSA/FSA reimbursement only)
Cancelling
Payment and Refund Policy (updated 2026-07-28): cancel via the option in account settings or by emailing support@onetwenty.com. The annual membership renews automatically. A refund is available only within 7 days of purchase and only if no service has started, minus a 3% fee. After that the annual fee is non-refundable, except for a discretionary prorated refund if no lab is reachable. Medication add-ons are non-refundable once prescribed.
Where it is available
Site FAQ: 'available in 49 states except for Rhode Island'; NY and NJ carry a higher fee ($749/yr) because of state lab-draw rules. DC not mentioned.
Data-driven clients who want extensive lab panels and coach-led, provider-supervised hormone optimization, and who will pay out of pocket without a clear upfront total.
- Starting price
- $299
- Consult model
- Video and asynchronous messaging
- Prescriber
- MD/DO + NP/PA
- Labs
- Billed separately
- Insurance
- Cash pay
- Availability
- 50 states
- Cancellation
- By email or written request
- Founded
- 2020 · Pontiac, MI
Pricing
Treatment pages show '$299' next to the Guided Optimization steps (coach assessment, lab analysis, a 25-minute licensed-provider consult, monthly coach check-ins) but never say whether it is one-time or recurring. They also state 'minimum $450 lab panel purchase required'. Medication prices are not published.
| Marek Health | $299 entry feePublished entry/membership fee. Required labs, prescriptions and supplements are billed separately. Main site specifies a $450 minimum lab purchase; confirm the selected package and current terms. |
|---|
Prices as listed on October 17, 2026. They change often; confirm at checkout.
What we like
- Named care team includes MDs and DOs (e.g. Medical Director Steven Campbell, MD) alongside DNPs, FNPs and a PA-C
- No set subscription plans; FAQ says clients can cancel whenever they want
- Detailed published monitoring requirements: follow-up labs at 6-12 weeks, then every 6 months, plus an annual in-person physical
- Trustpilot 4.9 from 989 reviews; BBB A+ with 2 complaints in 3 years
Watch out for
- Lab panel is a separate purchase (minimum $450) and outside lab results are not accepted to start
- Medication prices are not published, and the meaning of the $299 figure is not explained
- All web sales are final and non-refundable
- Requires an in-person physical exam from an outside clinician every 12 months
Cancelling
FAQ: 'we don't offer any set subscription plans and you can cancel whenever you want.' Cancellation & Refund Policy: 'All Marek Health web sales are final and non-refundable'. The booking payment is a non-refundable deposit toward the provider exam. Appointment changes need 24 hours' notice by email, text or phone, or a fee of up to $50 may apply; no-shows may also be charged up to $50.
Where it is available
FAQ: Guided Optimization 'is available in all 50 states across the United States. However, specific treatments and diagnostics may be limited to certain states.' DC is not mentioned in the FAQ (the sign-up form's state list includes DC).
Ways2Well
Texas-rooted, cash-pay patients interested in lab-driven longevity, hormone and peptide care who want bundled bloodwork and do not need medication costs up front.
- Starting price
- $125/mo Core care plan
- Consult model
- Live video consult
- Prescriber
- Unconfirmed
- Labs
- Included
- Insurance
- Cash pay
- Availability
- 47 states
- Cancellation
- Minimum term or retention process
- Founded
- 2018 · Austin, TX
Pricing
Core costs $125/mo or $1,499/yr and includes 2 comprehensive panels plus 1 targeted panel, 4 x 40-minute clinician consults, app access and 15% off prescriptions and supplements; prescriptions are not included. Clarity is a one-time $499 for 1 panel and a 40-minute video consult. Peptide therapy needs a separate $99 consult, and peptides are bought separately.
Prices as listed on October 17, 2026. They change often; confirm at checkout.
What we like
- Lab panels are included in the Core ($125/mo) and Clarity ($499) care plans
- Publishes a detailed state list with service-specific restrictions (46 states + DC)
- Free 20-minute RN phone call (Connect) before committing
- In-person locations in Austin and Houston alongside telehealth
Watch out for
- Medications and peptides are not included in plan prices, and peptide prices are not published
- Monthly Core requires a minimum of two billing cycles, and fees are non-refundable
- BBB rating of F for the 'Ways2Well - Austin' listing (3 complaints in 3 years); Trustpilot 3.1
- Cash-pay only: not contracted with any insurer, and no CPT/ICD-10 codes provided
Cancelling
You can cancel through the online account or app, or by contacting support. Monthly Core memberships require at least two billing cycles, and the next scheduled payment is still charged after a cancellation request. Annual plans run to the renewal date with no refund. Care-plan fees, labs and consultations are non-refundable.
Where it is available
The covered-states page lists 46 states plus DC. Missouri, New Jersey, New York and Rhode Island are on a waitlist. Testosterone is unavailable in 13 states (AL, AR, CT, GA, ID, LA, MI, NH, ND, OK, PA, SC, WV), leaving 34 jurisdictions for TRT. The peptide page lists 44 jurisdictions, and CA, OH and NV get weight-loss peptides only.
Men in one of the 34 eligible states who are willing to prepay several months of TRT to get a lower monthly price that includes medication and follow-up labs.
- Starting price
- $99/mo TRT on a 12-month plan
- Consult model
- Video and asynchronous messaging
- Prescriber
- MD/DO + NP/PA
- Labs
- Billed separately
- Insurance
- Cash pay
- Availability
- 34 states
- Cancellation
- Minimum term or retention process
- Founded
- 2021 · Nashville, TN
Pricing
TRT tiers are Flex at $149/mo (3-month commitment, $447 upfront), Commit & Save at $129/mo (6 months, $774 upfront) and Full Year at $99/mo (12 months, $1,188 upfront). The page says the fee covers medications, clinician consults and follow-up labs. A lab panel and clinician visit are required before starting: the Complete Hormone Panel is $149 and the Advanced Panel is $399, and an at-home phlebotomist costs $99 where available.
Prices as listed on October 17, 2026. They change often; confirm at checkout.
What we like
- TRT tiers, lab panel prices and restricted states are all published on the product page
- The monthly TRT fee covers medication, clinician consults and quarterly follow-up labs
- BBB A+ and accredited with 0 complaints in 3 years; Trustpilot 4.5 from 1,433 reviews
- Patients can choose asynchronous or synchronous consultations
Watch out for
- The advertised $99/mo TRT price requires paying 12 months ($1,188) upfront; the shortest plan is 3 months at $149/mo
- Initial labs are extra ($149-$399), and all sales are non-refundable
- TRT is unavailable in 16 states, including PA, NC, GA and MN
- Does not bill insurance; peptides and labs are not covered
Cancelling
TRT plans are sold with 3-, 6- or 12-month commitments paid upfront. The Terms also require at least three consecutive months of subscription and an email cancellation at least 30 days before the next processing date, but that section is bracketed and may be draft text. The help center says subscriptions can be cancelled any time in the Patient Portal (Home > Subscriptions) before the next renewal date. All sales are final: medication, subscription and lab payments are not refunded.
Where it is available
TRT cannot be prescribed or shipped to AL, AR, CT, DE, GA, HI, LA, MN, MO, MS, NC, ND, OK, PA, RI or SC (16 states), which leaves 34 states. The help center says testing and treatment are offered 'in all fifty states' across its therapies. DC is not mentioned for TRT.
Defy Medical
Self-pay patients who want long video consultations and a la carte hormone, weight-loss or peptide care without a subscription, and who can tolerate unpublished per-visit pricing.
- Starting price
- Under $175/mo average for TRT in year one
- Consult model
- Live video consult
- Prescriber
- MD/DO + NP/PA
- Labs
- Billed separately
- Insurance
- Cash pay
- Availability
- Unconfirmed
- Cancellation
- No subscription to cancel
- Founded
- Tampa, FL
Pricing
Defy's FAQ estimates male TRT averages under $175/month in the first year and about $125/month after that. The estimate covers testosterone, a weekly aromatase inhibitor, labs and consultations, and Defy says it is not a price guarantee. There is no monthly fee: consultations, labs and medications are each paid for when bought. No consultation fee is published on Defy's site.
Prices as listed on October 17, 2026. They change often; confirm at checkout.
What we like
- No subscription, monthly fee or contract; patients pay only for the services they buy
- Initial consultations by secure video last up to one hour, and follow-ups up to 30 minutes
- Care team of physicians, physician assistants and nurse practitioners, plus an in-person clinic in Tampa
- Trustpilot score of 4.8 from 4,221 reviews
Watch out for
- No consultation, lab or medication prices on the main site; only an average monthly TRT estimate
- Does not accept insurance of any kind (it provides a superbill on request)
- Its Peptide Therapy service page features BPC-157, TB-500, Epitalon, KPV and MOTS-c, which are on FDA's 503A Category 2 safety-risk list
- BBB rating of C- (not accredited), with 4 complaints in the last 3 years
Cancelling
No subscription or contract: 'Defy Medical doesn't lock patients into subscriptions or contracts', and charges are due when a service is purchased, so there is no recurring plan to cancel. Appointments cancelled with less than 24 hours' notice, and no-shows, may be charged the full consultation fee. Sales are generally final. Lab orders are refundable only before specimens are submitted, and dispensed medications are not refundable.
Where it is available
Says telemedicine is offered in 'most states throughout the US' without listing them. Its lab-ordering site (testdefy.com) says on-demand lab testing is not offered in NY, NJ, PA, RI or MA. The ToS says controlled-substance prescriptions are not sent across state lines.
Head-to-head comparisons
Tools for this decision
How we ranked these
Same rubric. Clinics advertising Category 2 compounds are excluded. Facts come from each provider’s own pricing, FAQ and terms pages, with regulator and court records where they exist. Scores are produced by a fixed table, so the same facts always give the same score. See the rubric.
Best peptide therapy clinics: FAQ
What is the best peptide therapy clinics provider?
OneTwenty ranks first, scoring 9.9/10 on our five-criterion rubric. People who want their blood retested every 90 days (a 101-marker baseline plus three follow-up panels a year) and want custom supplements and prescriptions, at published prices, driven by those results in one membership.
How were these providers ranked?
Every provider is scored on the same five weighted criteria: licensed states (24%), labs included (24%), cost transparency (18%), cancellation friction (17%) and formulary breadth (17%). Who prescribes is shown on each review but not scored. Facts come from each provider’s published pages, checked November 6, 2026. Scores marked * are provisional because one or two criteria could not be verified.
Which of these include lab work in the price?
OneTwenty, Ways2Well include the initial lab work in their published pricing. The others bill labs separately or did not publish it.
Do providers pay to be on this list?
No. Placement is set by the rubric score. Where a provider pays us a referral fee, its link is labelled “Paid link”, and that does not change its score.