Peptide therapy telehealth
Which clinics prescribe peptides legally, and what is actually on their formulary.
6 providers offer this. 2 include labs in the price. 0 accept insurance. Figures reflect what each provider publishes. * = provisional score.
Highest-scored providers
#1 Marek Health 7.1 
Blokes 6.3 
OneTwenty 9.2*
Data-driven clients who want extensive lab panels and coach-led, provider-supervised hormone optimization, and who will pay out of pocket without a clear upfront total.
Read the review → #2 Blokes 6.3 Men in one of the 34 eligible states who are willing to prepay several months of TRT to get a lower monthly price that includes medication and follow-up labs.
Read the review → #3 OneTwenty 9.2* People who mainly want frequent longevity lab testing and wearable data tracking, accept an upfront non-refundable annual fee, and treat prescriptions as an optional add-on.
Read the review →Ranked guides
All providers
| Clinic | Score | Consult | Labs | Prescriber | Insurance | From |
|---|---|---|---|---|---|---|
| Marek Health Also offers A telehealth clinic built around comprehensive bloodwork and physician-guided hormone optimisation, with TRT, peptide therapy and GLP-1 programmes. Known for an unusually deep lab panel. | 7.1 | Hybrid | Extra | MD/DO + NP/PA | Cash | $299 |
| Blokes Also offers A men’s telehealth clinic offering TRT, peptide therapy, GLP-1 weight loss and sexual health, with a sister brand for women. | 6.3 | Hybrid | Extra | MD/DO + NP/PA | Cash | $99/mo TRT on a 12-month plan |
| OneTwenty Also offers Bloodwork-led longevity and hormone optimisation telehealth, with physician-guided TRT, GLP-1 weight management and peptide therapy built on comprehensive lab panels. | 9.2* | — | Included | — | Cash | $499/yr membership |
 Defy Medical Also offers One of the longest-running hormone telehealth clinics, offering TRT, HRT for women, peptide therapy and sexual health treatments with physician oversight. | 6.9* | Video | Extra | MD/DO + NP/PA | Cash | Under $175/mo average for TRT in year one |
 Ways2Well Also offers A functional-medicine telehealth clinic offering bloodwork-driven hormone optimisation, TRT, peptide therapy and GLP-1 weight loss. | 6.8* | Video | Included | — | Cash | $125/mo Core care plan |
 Joi Also offers A women’s hormone telehealth clinic, sister brand to Blokes, offering HRT, peptide therapy and GLP-1 weight loss. | 6.2* | Hybrid | Extra | — | Cash | $149 hormone lab panel |
Head-to-head comparisons
Tools for this decision
What these clinics prescribe
Reference records for the compounds offered in this category. Mechanism, dosing ranges, evidence level and regulatory status for each.
- Gonadorelin — Synthetic gonadotropin-releasing hormone, increasingly used alongside TRT to maintain testicular function.
- hCG — A placental glycoprotein hormone that mimics LH directly at the testis, the long-standing standard for preserving fertility on TRT.
- PT-141 — A melanocortin-4 selective agonist approved for hypoactive sexual desire disorder, acting centrally rather than vascularly.
- Semaglutide — A long-acting GLP-1 receptor agonist and the compound that reset expectations for pharmacological weight loss.
- Sermorelin — The first 29 amino acids of endogenous growth-hormone-releasing hormone, and the shortest fragment that retains full biological activity.
- Tesamorelin — A stabilised GHRH analog and the only growth-hormone secretagogue with a current FDA approval for a body-composition indication.
- Tirzepatide — A dual GIP and GLP-1 receptor agonist that produced greater weight loss than semaglutide in head-to-head trial data.
References
Regulatory and primary sources
- FDA: Bulk drug substances that may present significant safety risks (Category 2 and withdrawn nominations) ↗ · content current as of April 22, 2026; checked October 18, 2026
- FDA: Bulk drug substances used in compounding under section 503A ↗ · how the 503A categories work
- HHS: Telehealth for patients ↗ · what to expect from a telehealth visit
- FDA: BeSafeRx, buying medicine online safely ↗ · how to check an online pharmacy
- NABP: Safe.Pharmacy verified websites ↗ · pharmacy accreditation lookup
- FSMB DocInfo: physician license lookup ↗ · check a prescriber is licensed
- FTC: Endorsements, influencers and reviews ↗ · disclosure rules for affiliate links
Published literature
- Peptide therapeutics: current status and future directions.Drug Discov Today 2015.PubMed 25450771 · doi:10.1016/j.drudis.2014.10.003
- Therapeutic peptides: current applications and future directions.Signal Transduct Target Ther 2022.PubMed 35165272 · doi:10.1038/s41392-022-00904-4
- Advances in oral peptide therapeutics.Nat Rev Drug Discov 2020.PubMed 31848464 · doi:10.1038/s41573-019-0053-0
- Injectable Therapeutic Peptides-An Adjunct to Regenerative Medicine and Sports Performance?.Arthroscopy 2025.PubMed 39265666 · doi:10.1016/j.arthro.2024.09.005
- Therapeutic peptides: Historical perspectives, current development trends, and future directions.Bioorg Med Chem 2018.PubMed 28720325 · doi:10.1016/j.bmc.2017.06.052
- Peptide chemistry toolbox - Transforming natural peptides into peptide therapeutics.Bioorg Med Chem 2018.PubMed 29395804 · doi:10.1016/j.bmc.2018.01.012
- Oral delivery of therapeutic peptides and proteins: Technology landscape of lipid-based nanocarriers.Adv Drug Deliv Rev 2022.PubMed 34999121 · doi:10.1016/j.addr.2021.114097
- Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions.J Am Acad Orthop Surg Glob Res Rev 2026.PubMed 41490200 · doi:10.5435/JAAOSGlobal-D-25-00236
Literature retrieved from PubMed on October 18, 2026, favouring human studies and reviews. Numbered markers in the text show which paper supports which statement; uncited entries are background reading.