5-Amino-1MQ [Ultimate Guide]

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Only a few peptides have come on the market that can effectively assist you in weight loss, and one such peptide is 5-Amino-1MQ.

People often associate synthetic peptides with muscle building, optimal body growth, and enhanced athletic performance, and rightly so because most peptides are synthesized to work that way. 

The weight loss journey can be daunting but is an important road. Excess body weight or obesity is one of the most common causes of major cardiovascular disorders.

Winner: Best Weight Loss Peptide
5-Amino-1MQ 3000mg Peptide | Lab Tested Fast Shipping
  • 6% drop in bodyweight in 11 days.
  • Cholesterol dropped 30%
  • Fat cell size decreased.
  • The ability for lipogenesis decreased ~70%.
  • 5A1MQ is orally bioavailable.
  • Long lasting increases in NAD+.
  • Pricing and dosage can be prohibitive for some
Learn More

Most of us may believe that hitting gym sessions persistently and making significant dietary changes can put us back on track regarding our weight. Reversing the obesity symptoms but trust me, many times, it’s not enough, and this is where peptides like 5-Amino-1MQ come into play!

Read through the end to learn about 5-Amino-1MQ, such as how it works, the potential benefits, possible adverse effects, and dosage recommendations.

What is 5-Amino-1MQ? 

5-Amino-1MQ, a peptide derivative of methylquinolinium, is often vouched as a potent weight loss treatment and anti-obesity medication.

What is 5-Amino-1MQ

This molecular drug is a small and selectively permeable molecule that acts as a nicotinamide N-methyltransferase (NNMT) inhibitor. 

NNMT is an enzyme abundantly found in the cytoplasm and is responsible for energy homeostasis and other metabolic processes occurring inside the cells, particularly in adipocytes.

How Does 5-Amino-1MQ work?

5-Amino-1MQ is selectively permeable in nature; thus, it enters the cytoplasm and blocks the activity of NNMT. Subsequent inhibition results in increased cellular levels of nicotinamide adenine dinucleotide (NAD+), the latter being the key regulator of energy metabolism.

How Does 5-Amino-1MQ work

Downregulation of NNMT also activates Sirtuin-1 (SIRT-1), a gene known to promote “anti-aging” effects. 

Knowing this exact mechanism of action followed by the peptide makes it easier to understand its benefits. 

5-Amino-1MQ Benefits 

While most of the 5-Amino-1MQ benefits revolve around weight loss and mitigating the risk of associated disorders, we will explore the scientifically and anecdotally proven benefits one by one. 

Promotes Weight Loss

Increased NAD+ levels enhance overall cellular metabolism, particularly in the fat cells, and upregulates the basal metabolic rate (BMR). Thus, an increased energy utilization ultimately results in fat loss. 

Because 5-Amino-1MQ suppresses the activity of NNMT, this also results in shrinkage of fat deposits, further contributing to fat burn and subsequent weight loss (1). One of the mice-based studies confirmed the fat loss effect where the subjects experienced a 7% reduction in total body mass after administering the peptide. 

Promotes Weight Loss

5-Amino-1MQ is also known to suppress the process of lipogenesis and prevent any possible fat accumulation. 

Prevents Metabolic Syndrome

Because 5-Amino-1MQ promotes excess fat burn, prevents fat accumulation, and reverses diet-induced obesity pretty effectively, this eventually reduces the risk of developing metabolic syndromes such as diabetes, hypertension, atherosclerosis, and other major cardiovascular disorders. 

Increasing Lean Muscle Mass 

The downregulation of NNMT also promotes the regeneration of muscle tissue and prevents muscular dystrophy or muscle wasting (2). Some users have also reported an improved recovery post-workout sessions.  

Besides, 5-Amino-1MQ is known to promote cell proliferation, thus ensuing in enhanced capability to contract the muscles. You may also expect improved athletic performance and increased endurance after using 5-Amino-1MQ. 

Treating Other Medical Conditions 

Researchers also hypothesize the potent role of 5-Amino-1MQ in decreasing the risk of developing major hepatic, renal, and neurological complications. 

Besides, elevated NNMT levels are one of the contributing factors in the pathophysiology of gastric cancers. Because 5-Amino-1MQ inhibits the activity of NNMT, it may have some role in suppressing certain types of cancer. 

All these benefits correlate to the fact that 5-Amino-1MQ possesses anti-inflammatory and anti-oxidant properties. 

Anti-Aging Effects 

Activation of the SIRT-1 gene implies that one may enjoy the benefits of increased life span and minimal possibility of developing many chronic conditions.

5-amino 1mq peptide side effects

Due to the targetted action of 5-Amino-1MQ, there are no significant risks of developing any major adverse effects. 

5-amino 1mq peptide side effects

Nonetheless, some users have reported that dosing the peptide too late interrupts their normal circadian rhythm, and they experience difficulty falling asleep. 

Also, if you are pregnant or using any other medications, consult your primary physician before using the peptide, as it may have adverse interactions. 

5-Amino-1MQ Dosage and Cycle 

Most users have seen optimal weight loss results when taking 50mg of 5-Amino-1MQ three times per day. We recommend using this peptide for at least two months, followed by a month’s break.

5-Amino-1MQ Dosage and Cycle 

Also, try using the peptide with your meals to ensure better bioavailability. 

Forms of 5-Amino-1MQ Available 

While most peptides are usually available in powder form, you will only find the capsule form of 5-Amino-1MQ available at reputable stores.

5-Amino-1MQ Before and After

On average the before and after the progress of taking 5-Amino-1MQ is substantial.

Users often see a 6% to 7% loss in body fat in the first 3 – 5 weeks after taking this peptide. If you are looking to cut weight for a competition or your sport of choice 5-Amino-1MQ is a no-brainer.

This peptide will help you get rid of that last bit of stubborn fat in the midsection and have your abs shredded on contest day.

5-Amino-1MQ Where to Buy Online

There are several places to buy 5-Amino-1MQ online.

Remember, all online peptide stores are not created equal.

Lindy Health went above and beyond and ordered from several online 5-Amino-1MQ suppliers in order to find the best in purity, price, and delivery for peptides.

Swiss Chem is the best place to buy 5-Amino-1MQ that we found online:

Winner: Best Weight Loss Peptide
5-Amino-1MQ 3000mg Peptide | Lab Tested Fast Shipping
  • 6% drop in bodyweight in 11 days.
  • Cholesterol dropped 30%
  • Fat cell size decreased.
  • The ability for lipogenesis decreased ~70%.
  • 5A1MQ is orally bioavailable.
  • Long lasting increases in NAD+.
  • Pricing and dosage can be prohibitive for some
Learn More


The price of 5-Amino-1MQ varies depending on the quality, amount, and how quickly you would like your peptides shipped.

We found on average 5-Amino-1MQ’s price is around $150 US to $300 US on most online peptide stores.

Tailor Made Capsules

We found that Swiss Chem’s tailor-made 5-Amino-1MQ capsules are the best when it comes to quality, purity, and pricing.

Frequently Asked Questions

How long do you take 5-Amino-1MQ? 

You may start noticing the results within the first three months of use. Perhaps it is advisable to use it repeatedly for two months followed by a month’s break till you have lost your desired weight. 

What peptides are best for weight loss? 

Apart from 5-Amino-1MQ, research has proven that Tesamorelin, CJC-1295, and AOD 9604 are the most potent peptides for triggering weight loss

What type of diet can you be on while using 5-Amino-1MQ? 

Using it with a caloric-deficit diet or ketogenic diet can prove efficacious in fat burning and weight loss. 

Is there a 5-amino 1mq forum?

Yes, there are several online forums that cover the topic of 5-amino-1mq. Check out the Ray Peat Forum, UG Bodybuilding Forum, or the Iron Den.

Can I buy 5-amino-1MQ in bulk?

Yes, you can order 5-amino-1MQ in bulk from Swiss Chems, Chemyo, and several other online peptide providers.

Can I buy 5-amino-1MQ on Amazon?

No, at this time 5-amino-1MQ does not appear to be available for sale on Amazon.

How are the 5-amino-1MQ reviews?

The reviews for 5-amino-1MQ are overwhelmingly positive on both Google and online peptide forums. Always do your own research but we believe that this peptide works well and anecdotally brings users results.

In a Nutshell 

5-Amino-1MQ is a substantially researched peptide and has proven efficacious in promoting fat burn and stimulating weight loss. This peptide increases the intracellular levels of NAD+, the primary regulator of energy metabolism. 

Not only this, but 5-Amino-1MQ offers systemic benefits by blocking NNMT, and this alleviates the risk of developing other chronic disorders and ensures that you enjoy a longer life span. 

It’s not just the medical research that affirms the benefits of 5-Amino-1MQ. Still, after reading users’ experiences and reviews on Reddit and other platforms, I can surely recommend using 5-Amino-1MQ as your perfect weight loss companion! 


  1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5826726/
  2. https://pubmed.ncbi.nlm.nih.gov/27798264/
Dr. Ian Nellis MD
Latest posts by Dr. Ian Nellis MD (see all)

Dr. Ian Nellis MD

Dr. Ian Nellis is a medical doctor with over ten years of experience in the health care industry. Dr. Nellis is passionate about sports nutrition and helping his patients live healthy and fulfilling lives. He lives and practices medicine in Denver, CO, with his wife and beloved Mastiff Leonardo.

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