Key findings
- Between 30 million and 50 million men in the United States have erectile dysfunction, according to NIDDK.
- About 40% of men are affected by ED at age 40, and 70% report having ED by age 70.
- Only 25.4% of 6,228,509 US men diagnosed with ED filled a prescription for treatment in a year.
- PDE5 inhibitors have a discontinuation rate of about 4% per month, almost 50% after one year.
- Men with ED had a pooled relative risk of 1.44 for cardiovascular events in a meta-analysis of 14 cohort studies.
How many men have erectile dysfunction?
men in the United States have erectile dysfunction1
of US men aged 20 and older have erectile dysfunction, suggesting ED affects 18 million US men2
Nationally representative NHANES data from 2001-2002 (2,126 men).
of men aged 40 to 70 had some degree of erectile dysfunction (minimal, moderate or complete)3
Massachusetts Male Aging Study, a community-based sample surveyed in 1987-1989.
men worldwide were projected to have ED by 2025, up from over 152 million in 19954
is the range of ED prevalence reported across population-based studies worldwide5
The wide range largely reflects different screening questionnaires.
How common is erectile dysfunction by age?
of men are affected by erectile dysfunction at age 401
of men report having erectile dysfunction by age 701
rise in the prevalence of complete erectile dysfunction between ages 40 and 70, a tripling3
of men aged 70 or older had erectile dysfunction in a Minnesota community cohort, vs 2% of men aged 40 to 496
Olmsted County, Minnesota, 1,402 men with regular sexual partners screened 1996-2005; prevalence was 6% at 50-59 and 17% at 60-69.
of men seeking first medical help for new-onset ED were aged 40 or younger7
Single-center study of 439 consecutive patients in Italy; 48.8% of the younger men had severe ED.
of US men with diabetes have erectile dysfunction (crude prevalence)2
NHANES 2001-2002.
How many men with ED get treatment?
of 6,228,509 US men diagnosed with ED were treated during a 12-month period8
Commercial insurance claims for the 12 months ending June 2011; treated meant filling a prescription for a PDE5 inhibitor, injection or urethral therapy, or testosterone.
of treated men with ED received PDE5 inhibitors, the most common medical therapy8
Testosterone was used alone or in combination in 30.6% of treated men.
is the average discontinuation rate for PDE5 inhibitors (sildenafil, vardenafil, tadalafil), almost 50% after one year9
Meta-analysis of 22 observational studies with 162,936 patients; partner-related problems and lack of efficacy were the most important reasons.
is the year the FDA approved Viagra (sildenafil), the first PDE5 inhibitor for ED10
Original approval dated March 27, 1998.
is the year the FDA approved Cialis (tadalafil)11
Original approval dated November 21, 2003.
estimated US prescriptions for sildenafil in 2024, for an estimated 1,358,815 patients12
Derived from the Medical Expenditure Panel Survey; includes sildenafil prescribed for pulmonary arterial hypertension. Average out-of-pocket cost was $17.42 per prescription.
estimated US prescriptions for tadalafil in 2024, for an estimated 1,448,599 patients13
Derived from the Medical Expenditure Panel Survey; includes tadalafil prescribed for enlarged prostate and pulmonary arterial hypertension. Average out-of-pocket cost was $22.35 per prescription.
Is erectile dysfunction linked to heart disease?
hazard ratio for subsequent cardiovascular events in men aged 55 and older with incident or prevalent ED14
Placebo arm of the Prostate Cancer Prevention Trial (9,457 men, 1994-2003); new-onset ED alone carried a hazard ratio of 1.25.
of men aged 55 and older without ED at study entry reported new ED within 5 years14
2,420 of 4,247 men in the Prostate Cancer Prevention Trial placebo group.
pooled relative risk of cardiovascular events for men with vs without ED15
Meta-analysis of 14 cohort studies (92,757 participants). Pooled relative risks were 1.62 for heart attack and 1.39 for stroke; risk was higher at younger ages.
pooled relative risk of death from any cause for men with vs without ED15
of men with chest pain and angiographically documented coronary artery disease had ED16
300 consecutive patients in Milan, Italy.
of men with both ED and coronary artery disease reported that ED symptoms appeared before heart symptoms16
The mean interval between ED onset and coronary artery disease was 38.8 months.
new coronary artery disease cases per 1,000 person-years among men aged 40 to 49 with vs without ED6
Olmsted County, Minnesota cohort. ED was of little prognostic importance in older men.
How do men use telehealth for ED treatment?
patients treated with sildenafil, tadalafil or vardenafil were analyzed from a direct-to-consumer telemedicine platform database17
Adverse event rates at medium and high doses were 35.0% for sildenafil, 33.9% for tadalafil and 47.4% for vardenafil; nasal congestion was most common.
of 497 men who got sexual health treatment through a national US direct-to-consumer telehealth platform reported favorable impressions of care quality and safety on most survey items18
Online survey of platform users, June 30 to July 3, 2025.
subscribers used Hims & Hers, a telehealth platform whose treatments include sexual health and hair loss, at the end of June 202619
Up 19% year over year. The company does not break out subscribers by condition.
Erectile dysfunction statistics: FAQ
How common is erectile dysfunction?
NIDDK estimates that between 30 million and 50 million US men have ED. National survey data found 18.4% of US men aged 20 and older have ED, and the Massachusetts Male Aging Study found 52% of men aged 40 to 70 had some degree of ED.
At what age does erectile dysfunction start?
ED becomes more common with age: about 40% of men are affected at age 40 and 70% report ED by age 70, according to NIDDK. It also affects younger men; in one clinic study, 26% of men seeking first help for new ED were 40 or younger.
How many men with ED get treated?
In a claims analysis of 6,228,509 insured US men diagnosed with ED, only 25.4% filled a prescription for treatment within a year. PDE5 inhibitors made up 75.2% of treatment, and about half of PDE5 inhibitor users stop within a year.
Is erectile dysfunction a sign of heart disease?
ED is linked to higher cardiovascular risk. A meta-analysis of 14 studies found a pooled relative risk of 1.44 for cardiovascular events in men with ED, and in men with coronary artery disease, 67% reported ED symptoms before heart symptoms by a mean of 38.8 months.
When was Viagra approved?
The FDA approved Viagra (sildenafil) on March 27, 1998 and Cialis (tadalafil) on November 21, 2003.
Sources
- Definition & Facts for Erectile Dysfunction. National Institute of Diabetes and Digestive and Kidney Diseases (NIH), 2024. government
- Prevalence and risk factors for erectile dysfunction in the US (Selvin E et al.). American Journal of Medicine, 2007. peer-reviewed
- Impotence and its medical and psychosocial correlates: results of the Massachusetts Male Aging Study (Feldman HA et al.). Journal of Urology, 1994. peer-reviewed
- The likely worldwide increase in erectile dysfunction between 1995 and 2025 and some possible policy consequences (Ayta IA et al.). BJU International, 1999. peer-reviewed
- The global prevalence of erectile dysfunction: a review (Kessler A et al.). BJU International, 2019. peer-reviewed
- A population-based, longitudinal study of erectile dysfunction and future coronary artery disease (Inman BA et al.). Mayo Clinic Proceedings, 2009. peer-reviewed
- One patient out of four with newly diagnosed erectile dysfunction is a young man (Capogrosso P et al.). Journal of Sexual Medicine, 2013. peer-reviewed
- Undertreatment of erectile dysfunction: claims analysis of 6.2 million patients (Frederick LR et al.). Journal of Sexual Medicine, 2014. peer-reviewed
- First-generation phosphodiesterase type 5 inhibitors dropout: a comprehensive review and meta-analysis (Corona G et al.). Andrology, 2016. peer-reviewed
- Drugs@FDA: Viagra, NDA 020895. US Food and Drug Administration (Drugs@FDA), 1998. government
- Drugs@FDA: Cialis, NDA 021368. US Food and Drug Administration (Drugs@FDA), 2003. government
- Sildenafil - Drug Usage Statistics, United States, 2014 - 2024. ClinCalc DrugStats Database (based on AHRQ Medical Expenditure Panel Survey), 2026. industry
- Tadalafil - Drug Usage Statistics, United States, 2014 - 2024. ClinCalc DrugStats Database (based on AHRQ Medical Expenditure Panel Survey), 2026. industry
- Erectile dysfunction and subsequent cardiovascular disease (Thompson IM et al.). JAMA, 2005. peer-reviewed
- Prediction of cardiovascular events and all-cause mortality with erectile dysfunction: a systematic review and meta-analysis of cohort studies (Vlachopoulos CV et al.). Circulation: Cardiovascular Quality and Outcomes, 2013. peer-reviewed
- Erectile dysfunction prevalence, time of onset and association with risk factors in 300 consecutive patients with acute chest pain and angiographically documented coronary artery disease (Montorsi F et al.). European Urology, 2003. peer-reviewed
- Head-to-head Comparison of the Safety and Efficacy Profiles of Three Phosphodiesterase Type 5 Inhibitors through Patient-reported Outcomes of 130 000 Patients from a Direct-to-consumer Platform Database (Rodler S et al.). European Urology Focus, 2026. peer-reviewed
- Individual Perceptions of the Efficacy, Quality, and Safety of Sexual Health Care Delivered via a Direct-to-Consumer Telehealth Platform (Bohl M et al.). JMIR Formative Research, 2026. peer-reviewed
- Hims & Hers Health, Inc. Reports Second Quarter 2026 Financial Results (Exhibit 99.1 to Form 8-K). Hims & Hers Health, Inc. (SEC filing), 2026. company-filing
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Lindy Health. “Erectile dysfunction statistics 2026: prevalence by age, treatment and heart health.” Updated October 18, 2026. https://lindyhealth.com/statistics/erectile-dysfunction-statistics/